{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T21:31:32Z","timestamp":1791754292315,"version":"4.3.4"},"reference-count":18,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T00:00:00Z","timestamp":1335744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Objective.<\/jats:italic>\n                    To compare maternal and neonatal outcomes of term large for gestational age (LGA) pregnancies and adequate for gestational age (AGA) pregnancies.\n                    <jats:italic>Design.<\/jats:italic>\n                    Retrospective analysis.\n                    <jats:italic>Setting.<\/jats:italic>\n                    Large university research medical center.\n                    <jats:italic>Population.<\/jats:italic>\n                    All term singleton LGA (birthweight \u226590th percentile) and AGA pregnancies (birthweight 10.1\u201389.9th percentile) delivering between 2004 and 2008.\n                    <jats:italic>Methods.<\/jats:italic>\n                    Data collected included maternal age, gestational age at delivery, mode of delivery, birthweight, fetal sex, and maternal and neonatal complications. Birthweight percentiles were determined according to locally derived gender\u2010specific birthweight tables.\n                    <jats:italic>Main outcome measures.<\/jats:italic>\n                    Comparisons between LGA and AGA pregnancies and between LGA 90\u201394.9th, 95\u201398.9th and \u226599th percentile.\n                    <jats:italic>Results.<\/jats:italic>\n                    The study population comprised 34\u00a0685 pregnancies; 3900 neonates matched the definition of term LGA. Maternal age and gestational age at delivery were significantly higher for LGA neonates. Significantly more LGA neonates were born by cesarean section, and significantly more LGA pregnancies were complicated by postpartum hemorrhage (PPH), shoulder dystocia or neonatal hypoglycemia, and had a longer hospitalization period. Maternal and neonatal risks increased as birthweight increased from the 90\u201394.9th to 95\u201398.9th to \u226599th percentile. Specifically, the risks of shoulder dystocia (odds ratio 2.61, 3.35 and 5.11, respectively), PPH (odds ratio 1.81, 2.12 and 3.92, respectively) and neonatal hypoglycemia (odds ratio 2.53, 3.8 and 5.19, respectively) all increased linearly with birthweight percentile.\n                    <jats:italic>Conclusions.<\/jats:italic>\n                    Large for gestational age pregnancies are associated with an increased rate of cesarean section, PPH, shoulder dystocia and neonatal hypoglycemia, as well as longer hospitalization. These risks increase as the birth percentile rises. These risks need to be emphasized in pre\u2010delivery counseling.\n                  <\/jats:p>","DOI":"10.1111\/j.1600-0412.2012.01412.x","type":"journal-article","created":{"date-parts":[[2012,4,4]],"date-time":"2012-04-04T03:24:54Z","timestamp":1333509894000},"page":"844-849","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":175,"title":["Maternal and neonatal outcomes of large for gestational age pregnancies"],"prefix":"10.1111","volume":"91","author":[{"given":"ALINA","family":"WEISSMANN\u2010BRENNER","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MICHAL J.","family":"SIMCHEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ERAN","family":"ZILBERBERG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANAT","family":"KALTER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BOAZ","family":"WEISZ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"REUVEN","family":"ACHIRON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MORDECHAI","family":"DULITZKY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,4,30]]},"reference":[{"key":"e_1_2_8_2_2","first-page":"904","volume-title":"Williams obstetrics","author":"Cunningham FG","year":"2005"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016340801899289"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2008.156026"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.02.035"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.02.068"},{"key":"e_1_2_8_7_2","first-page":"311","article-title":"Birthweight standards in the live\u2010born population in Israel","volume":"7","author":"Dolberg S","year":"2005","journal-title":"Isr Med Assoc J."},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-008-0630-7"},{"key":"e_1_2_8_9_2","first-page":"378","article-title":"Macrosomic newborns: a 3\u2010year review","volume":"52","author":"Akin Y","year":"2010","journal-title":"Turk J Pediatr."},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02823.x"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2009.01052.x"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/01443610220141281"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(97)00242-X"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(03)00045-9"},{"key":"e_1_2_8_15_2","first-page":"1170","volume-title":"Williams obstetrics","author":"Cunningham FG","year":"2005"},{"key":"e_1_2_8_16_2","first-page":"656","article-title":"The delivery of macrosomic infants weighing 4500\u00a0g and more. A report of 61 cases","volume":"82","author":"Kra\u00efem J","year":"2004","journal-title":"Tunis Med"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016341003686099"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00005-C"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/01443610701195074"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0412.2012.01412.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0412.2012.01412.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T09:53:19Z","timestamp":1697363599000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0412.2012.01412.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,30]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["10.1111\/j.1600-0412.2012.01412.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0412.2012.01412.x","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,30]]},"assertion":[{"value":"2012-04-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}