{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T21:48:11Z","timestamp":1772747291360,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,6,8]],"date-time":"2005-06-08T00:00:00Z","timestamp":1118188800000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Ophthalmologica Scandinavica"],"published-print":{"date-parts":[[2005,6]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p><jats:bold>Purpose:\u2002<\/jats:bold>  <jats:bold>An immunological reaction to a bacterial antigen, such as <jats:italic>Mycobacterium tuberculosis<\/jats:italic> or <jats:italic>Propionibacterium spp.<\/jats:italic>, is suspected to be an initial mechanism in the disorder known as sarcoidosis. We investigated whether or not <jats:italic>P.\u2003acnes<\/jats:italic>, <jats:italic>P.\u2003granulosum<\/jats:italic> or <jats:italic>M.\u2003tuberculosis<\/jats:italic> are present in the vitreous fluid of eyes suffering from uveitis with sarcoidosis.<\/jats:bold> <\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold>  <jats:bold>Using polymerase chain reaction, we analysed the presence of <jats:italic>P.\u2003acnes<\/jats:italic>, <jats:italic>P.\u2003granulosum<\/jats:italic> and\/or <jats:italic>M.\u2003tuberculosis<\/jats:italic> DNA in vitreous samples taken from six eyes with sarcoidosis and six control eyes.<\/jats:bold> <\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold>  <jats:bold>Among the six uveitis eyes with sarcoidosis, we detected <jats:italic>P.\u2003acnes<\/jats:italic> DNA in two eyes, <jats:italic>P.\u2003granulosum<\/jats:italic> DNA in four eyes, and both <jats:italic>P.\u2003acnes<\/jats:italic> and <jats:italic>P.\u2003granulosum<\/jats:italic> DNA in one eye, but no <jats:italic>Propionibacterium spp.<\/jats:italic> in the control eyes. <jats:italic>M.\u2003tuberculosis<\/jats:italic> DNA was not present in any of the patient or control eyes.<\/jats:bold> <\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold>  <jats:bold>This is the first report indicating the presence of <jats:italic>Propionibacterium spp.<\/jats:italic> and\/or its DNA in the vitreous fluid of sarcoidic eyes with uveitis. This, therefore, supports the idea that <jats:italic>Propionibacterium spp.<\/jats:italic> are involved in the aetiology of uveitis in sarcoidosis.<\/jats:bold> <\/jats:p>","DOI":"10.1111\/j.1600-0420.2005.00449.x","type":"journal-article","created":{"date-parts":[[2005,6,8]],"date-time":"2005-06-08T14:57:54Z","timestamp":1118242674000},"page":"364-369","source":"Crossref","is-referenced-by-count":34,"title":["The presence of <i>Propionibacterium spp.<\/i> in the vitreous fluid of uveitis patients with 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