{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T03:24:54Z","timestamp":1779247494104,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,5,16]],"date-time":"2006-05-16T00:00:00Z","timestamp":1147737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Ophthalmologica Scandinavica"],"published-print":{"date-parts":[[2006,6]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p><jats:bold>Purpose:\u2002<\/jats:bold> To evaluate the use of sterilized, freeze\u2010dried amniotic membrane (FD\u2010AM) transplantation for pterygium surgery.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> This study involved a prospective, non\u2010comparative, interventional case series. Thirteen eyes of 13 patients with primary (eight eyes) or recurrent (five eyes) pterygium were studied. After excision of the pterygium fibrous tissues and application of intraoperative use of mitomycin\u2010C, sterilized FD\u2010AM was sutured over the bare scleral defect. The integrity of the FD\u2010AM graft, epithelialization over the FD\u2010AM, pterygium recurrence and postoperative complications were evaluated.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Postoperatively, the FD\u2010AM was well retained in all patients, and complete epithelialization over the transplanted membrane was achieved within 1\u20132\u2003weeks. All patients demonstrated early resolution of ocular inflammation and there was no recurrence of pterygium in any of the treated patients during the mean follow\u2010up of 13.9\u2003\u00b1\u20036.0\u2003months. No ocular complications were noted following transplantation.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Sterilized FD\u2010AM showed excellent biocompatibility on the human ocular surface. This novel and promising biomaterial may be a useful alternative to conjunctival grafting in the treatment of pterygium.<\/jats:p>","DOI":"10.1111\/j.1600-0420.2006.00667.x","type":"journal-article","created":{"date-parts":[[2006,5,16]],"date-time":"2006-05-16T15:37:11Z","timestamp":1147793831000},"page":"401-405","source":"Crossref","is-referenced-by-count":40,"title":["Novel clinical application of sterilized, freeze\u2010dried amniotic membrane to treat patients with pterygium"],"prefix":"10.1111","volume":"84","author":[{"given":"Takahiro","family":"Nakamura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsutomu","family":"Inatomi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiichi","family":"Sekiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonard P. 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