{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T19:24:29Z","timestamp":1773948269252,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,6,28]],"date-time":"2008-06-28T00:00:00Z","timestamp":1214611200000},"content-version":"vor","delay-in-days":148,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2008,2]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p><jats:bold>Purpose:\u2002<\/jats:bold> To compare the efficacy of the dispersive\u2010viscoadaptive soft\u2010shell technique using Viscoat<jats:sup>\u00ae<\/jats:sup> and Healon<jats:sup>\u00ae<\/jats:sup>5 to the dispersive\u2010cohesive soft\u2010shell technique in reducing corneal endothelial cell damage during cataract surgery.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> In this prospective randomized study, 207 eyes of 171 cataract patients underwent phacoemulsification using the dispersive\u2010viscoadaptive soft\u2010shell technique (V\u2010group, 102 eyes) with Viscoat and Healon5 or the dispersive\u2010cohesive soft\u2010shell technique (C\u2010group, 105 eyes) with Viscoat and a cohesive agent (Opegan\u2010Hi<jats:sup>\u00ae<\/jats:sup>). Each group was divided into two subgroups depending on the amount of ultrasound (%Min) used during phacoemulsification. Corneal endothelial cell density was examined preoperatively and 3\u2003months postoperatively. The endothelial cell loss was compared between the two groups, and also between the subgroups.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> The mean endothelial cell loss 3\u2003months after surgery was 8.4 \u00b1 5.6% standard deviation (SD) in the V\u2010group and 8.2 \u00b1 6.2% in the C\u2010group (<jats:italic>P\u2003=\u2003<\/jats:italic>0.787). In the subgroups with ultrasound of 10 %Min or less, the mean endothelial cell loss 3\u2003months after surgery was 6.6 \u00b1 4.6% in the V\u2010group and 5.5 \u00b1 5.0% in the C\u2010group (<jats:italic>P\u2003=\u2003<\/jats:italic>0.104). In the subgroups with ultrasound of over 10 %Min, this value was 10.6 \u00b1 6.3% in the V\u2010group and 11.9 \u00b1 5.7% in the C\u2010group (<jats:italic>P\u2003=\u2003<\/jats:italic>0.413). The correlation coefficient of the endothelial cell loss rate and %Min was 0.245 (<jats:italic>P\u2003<\/jats:italic>=<jats:italic>\u2003<\/jats:italic>0.0129) in the V\u2010group and 0.501 (<jats:italic>P\u2003<\/jats:italic>&lt;<jats:italic>\u2003<\/jats:italic>0.0001) in the C\u2010group.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> The dispersive\u2010viscoadaptive soft\u2010shell technique is as effective as the dispersive\u2010cohesive soft\u2010shell technique in protecting corneal endothelial cells during phacoemulsification regardless of the amount of ultrasound energy used.<\/jats:p>","DOI":"10.1111\/j.1600-0420.2007.01018.x","type":"journal-article","created":{"date-parts":[[2007,10,3]],"date-time":"2007-10-03T07:33:37Z","timestamp":1191396817000},"page":"65-70","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Soft\u2010shell technique using Viscoat<sup>\u00ae<\/sup> and Healon<sup>\u00ae<\/sup>5: a prospective, randomized comparison between a dispersive\u2010viscoadaptive and a dispersive\u2010cohesive soft\u2010shell technique"],"prefix":"10.1111","volume":"86","author":[{"given":"Masaki","family":"Sato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiho","family":"Sakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikako","family":"Yabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuro","family":"Oshika","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,6,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(99)80121-7"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01251-2"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01262-7"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(13)80376-8"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(00)00643-X"},{"key":"e_1_2_6_7_1","first-page":"179","volume-title":"Phacoemulsification 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