{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T16:39:53Z","timestamp":1789835993509,"version":"4.0.1"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,7,22]],"date-time":"2008-07-22T00:00:00Z","timestamp":1216684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p><jats:bold>Purpose:\u2002<\/jats:bold> To evaluate posterior capsule opacification (PCO) 2\u2003years after cataract surgery following implantation of a hydrophilic or a hydrophobic single\u2010piece acrylic intraocular lens (IOL) with a sharp edge.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Phacoemulsification cataract surgery was performed in one eye of 120 patients with senile cataract in this prospective study. They were randomized to implantation of either a hydrophilic acrylic IOL (BL27; Bausch &amp; Lomb, Rochester, NY, USA) or a hydrophobic acrylic IOL (AcrySof<jats:sup>\u00ae<\/jats:sup> SA60AT; Alcon Laboratories, Fort Worth, TX, USA). Two years after surgery, retroillumination images were obtained and PCO area and severity were evaluated using <jats:sc>pocoman<\/jats:sc> software. Best corrected visual acuity (VA) (both high\u2010contrast [100%] and low\u2010contrast [2.5%]), glare, laser flare and intraocular pressure were measured. Capsulotomy rates were recorded.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Patients implanted with the hydrophilic IOL had a greater percentage area and severity of PCO compared with patients with the hydrophobic IOL (p<jats:italic>\u2003<\/jats:italic>&lt;<jats:italic>\u2003<\/jats:italic>0.001). There was no difference in PCO between men and women in the hydrophilic group. However, in the hydrophobic group, women had significantly more PCO than men (p<jats:italic>\u2003<\/jats:italic>&lt;<jats:italic>\u2003<\/jats:italic>0.05). Patients with the hydrophobic acrylic IOL had better high\u2010 and low\u2010contrast visual activity (VA) (p<jats:italic>\u2003<\/jats:italic>&lt;<jats:italic>\u2003<\/jats:italic>0.01) and less glare (p<jats:italic>\u2003<\/jats:italic>&lt;<jats:italic>\u2003<\/jats:italic>0.001) than those with a hydrophilic acrylic IOL. Of the patients with the hydrophilic IOL, 42% underwent capsulotomy, compared with 10% in the hydrophobic group (p<jats:italic>\u2003<\/jats:italic>&lt;<jats:italic>\u2003<\/jats:italic>0.001).<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Two years after surgery, patients with the SA60AT hydrophobic acrylic IOL had less PCO and better high\u2010 and low\u2010contrast VA than patients with the BL27 hydrophilic acrylic IOL.<\/jats:p>","DOI":"10.1111\/j.1600-0420.2007.01094.x","type":"journal-article","created":{"date-parts":[[2008,7,22]],"date-time":"2008-07-22T17:08:39Z","timestamp":1216746519000},"page":"533-536","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Two\u2010year follow\u2010up of posterior capsule opacification after implantation of a hydrophilic or hydrophobic acrylic intraocular lens"],"prefix":"10.1111","volume":"86","author":[{"given":"Maria","family":"Kugelberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisela","family":"Wejde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hari","family":"Jayaram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotta","family":"Zetterstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,7,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003470050205"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.05.010"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.05.022"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/j.1755-3768.1992.tb02182.x","article-title":"Reactive formation of hyaluronic acid after small and large lens injury","volume":"70","author":"Fagerholm P","year":"1992","journal-title":"Acta Ophthalmol Scand"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.08.060"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90047-7"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01028-8"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.07.022"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.81.10.862"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.05.011"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.03.041"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(97)80026-0"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-0634"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.1997.tb00149.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(02)02051-5"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01019-7"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2006.00718.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(98)80323-4"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2004.00322.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2004.12.013"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(99)80132-1"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0420.2007.01094.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0420.2007.01094.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T22:29:40Z","timestamp":1696976980000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0420.2007.01094.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,22]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1111\/j.1600-0420.2007.01094.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0420.2007.01094.x","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,22]]},"assertion":[{"value":"2008-07-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}