{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T22:32:01Z","timestamp":1759617121504},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,11,14]],"date-time":"2005-11-14T00:00:00Z","timestamp":1131926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:p><jats:bold>Objective:\u2002<\/jats:bold> A polymorphism in the promoter region of the NPY gene at position \u2212399 C&gt;T was recently reported to be associated with schizophrenia in a Japanese population and with treatment refractory unipolar depression in a Swedish population. The objective of this study was to investigate potential associations between the polymorphism and three psychiatric disorders in a Danish population.<\/jats:p><jats:p><jats:bold>Method:\u2002<\/jats:bold> We investigated the occurrence of the polymorphism in patients with schizophrenia (<jats:italic>n<\/jats:italic>\u2003=\u2003291), unipolar depression (<jats:italic>n<\/jats:italic>\u2003=\u2003256) and panic disorder (<jats:italic>n<\/jats:italic>\u2003=\u2003142) compared with controls (<jats:italic>n<\/jats:italic>\u2003=\u2003716).<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> We detected the polymorphism \u2212399 C&gt;T at a frequency of 48% in controls. No significant differences were found between genotype or allele frequencies in controls vs. the patient groups.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> The lack of association between the \u2212399 C&gt;T polymorphism and schizophrenia, unipolar depression or panic disorder, respectively, suggests that the polymorphism is not involved in the etiology of these disorders in the Danish population.<\/jats:p>","DOI":"10.1111\/j.1600-0447.2005.00648.x","type":"journal-article","created":{"date-parts":[[2005,11,14]],"date-time":"2005-11-14T15:26:50Z","timestamp":1131982010000},"page":"54-58","source":"Crossref","is-referenced-by-count":21,"title":["No association between the \u2212399 C&gt;T polymorphism of the neuropeptide Y gene and schizophrenia, unipolar depression or panic disorder in a Danish population"],"prefix":"10.1111","volume":"113","author":[{"given":"C.","family":"Lindberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Koefoed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. 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