{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T15:55:45Z","timestamp":1771516545266,"version":"3.50.1"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,11,2]],"date-time":"2006-11-02T00:00:00Z","timestamp":1162425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:p><jats:bold>Objective:\u2002<\/jats:bold> While rates and correlates of comorbidity have been investigated in the early course of psychosis, little is known about comorbidity in the medium\u2010to\u2010longer term or its relationship with outcome.<\/jats:p><jats:p><jats:bold>Method:\u2002<\/jats:bold> A total of 182 first\u2010episode psychosis (FEP) patients who met DSM\u2010IV criteria for a current psychotic disorder 8\u2003years after index presentation were grouped according to concurrent comorbidity [no concurrent axis I disorder; concurrent substance use disorder (SUD); other concurrent axis I disorder; concurrent SUD and other axis I disorder]. Outcomes were compared between groups controlling for relevant covariates.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> As much as 39% met criteria for one or more concurrent axis 1 diagnoses. Comorbidity was associated with greater severity of general psychopathology, but not with measures of functioning, treatment or negative symptoms.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Specific combinations of comorbid disorders may influence patterns of psychotic symptomatology. 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