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TMS has been approved for TRD in Canada, Australia, New Zealand, the European Union and Israel, but not yet in the United States. DBS remains in the early stages of investigation.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> While additional studies are clearly warranted, treatments that directly stimulate the brain appear to hold great therapeutic promise for severe psychiatric disorders.<\/jats:p>","DOI":"10.1111\/j.1600-0447.2007.01033.x","type":"journal-article","created":{"date-parts":[[2007,5,23]],"date-time":"2007-05-23T05:58:06Z","timestamp":1179899886000},"page":"174-181","source":"Crossref","is-referenced-by-count":86,"title":["Neurostimulation therapies in depression: a review of new modalities"],"prefix":"10.1111","volume":"116","author":[{"given":"L. 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