{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:03:27Z","timestamp":1789142607116,"version":"build-2803163510"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2007,7,7]],"date-time":"2007-07-07T00:00:00Z","timestamp":1183766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2007,12]]},"abstract":"<jats:p><jats:bold>Objective:\u2002<\/jats:bold> Research in animals has shown that exposure to stressors during pregnancy is associated with offspring behavioural disorders. We aimed to study the effect of <jats:italic>in utero<\/jats:italic> exposure to the Chernobyl disaster in 1986, and maternal anxiety presumably associated with that exposure, on behaviour disorder observed at age 14.<\/jats:p><jats:p><jats:bold>Method:\u2002<\/jats:bold> Exposed (<jats:italic>n<\/jats:italic>\u2003=\u2003232) and non\u2010exposed Finnish twins (<jats:italic>n<\/jats:italic>\u2003=\u2003572) were compared. A semi\u2010structured interview was used to assess lifetime symptoms of depression, generalized anxiety disorder, attention deficit hyperactivity disorder, conduct disorder and oppositional defiant disorder symptoms.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Adolescents who were exposed from the second trimester in pregnancy onwards, had a 2.32\u2010fold risk (95% CI: 1.13\u20134.72) of having lifetime depression symptoms, an increased risk of fulfilling DSM\u2010III\u2010R criteria of a major depressive disorder (OR\u2003=\u20032.48, 95% CI: 1.06\u20135.7), and a 2.01\u2010fold risk (95% CI: 1.14\u20133.52) of having attention deficit hyperactivity disorder symptoms.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Perturbations in fetal brain development during the second trimester may be associated with the increased prevalence of depressive and attention deficit hyperactivity disorder symptoms.<\/jats:p>","DOI":"10.1111\/j.1600-0447.2007.01050.x","type":"journal-article","created":{"date-parts":[[2007,7,7]],"date-time":"2007-07-07T09:45:45Z","timestamp":1183801545000},"page":"438-446","source":"Crossref","is-referenced-by-count":73,"title":["Chernobyl exposure as stressor during pregnancy and behaviour in adolescent offspring"],"prefix":"10.1111","volume":"116","author":[{"given":"A. 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