{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T17:17:29Z","timestamp":1794244649549,"version":"4.9.0"},"reference-count":58,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,8,24]],"date-time":"2007-08-24T00:00:00Z","timestamp":1187913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2007,10]]},"abstract":"<jats:p><jats:bold>Objective:\u2002<\/jats:bold> Anxiety is commonly observed in schizophrenia, but its relationship with other features of illness is unclear.<\/jats:p><jats:p><jats:bold>Method:\u2002<\/jats:bold> We examined correlations between measures of anxiety, positive and negative symptoms, hope, psychosocial function and trauma history among 128 participants with schizophrenia or schizoaffective disorder. Cluster analyses were conducted to determine whether we could detect a subgroup with severe anxiety.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Higher levels of anxiety were associated with greater hallucinations, withdrawal, depression, hopelessness, better insight and poorer function. Cluster analyses produced three groups according to anxiety level: subclinical anxiety (<jats:italic>n<\/jats:italic>\u2003=\u200337), moderate anxiety (<jats:italic>n<\/jats:italic>\u2003=\u200355) and severe anxiety (<jats:italic>n<\/jats:italic>\u2003=\u200336). <jats:sc>anova<\/jats:sc> revealed that the severe anxiety group had more severe hallucinations, poorer psychosocial function and less hope than either of the other two groups. Self\u2010report of sexual trauma predicted higher levels of anxiety overall.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> A subgroup of persons with severe anxiety may be identifiable in schizophrenia with a unique clinical profile.<\/jats:p>","DOI":"10.1111\/j.1600-0447.2007.01067.x","type":"journal-article","created":{"date-parts":[[2007,8,24]],"date-time":"2007-08-24T11:10:24Z","timestamp":1187953824000},"page":"290-298","source":"Crossref","is-referenced-by-count":154,"title":["Anxiety symptoms in schizophrenia spectrum disorders: associations with social function, positive and negative symptoms, hope and trauma history"],"prefix":"10.1111","volume":"116","author":[{"given":"P. H.","family":"Lysaker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. P.","family":"Salyers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,8,24]]},"reference":[{"key":"e_1_2_7_2_2","volume-title":"Dementia praecox or the group of schizophrenias","author":"Bleuler E","year":"1950"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0010-440X(95)90092-A"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1987.tb02806.x"},{"key":"e_1_2_7_5_2","first-page":"437","article-title":"Obsessive compulsive disorder in patients with schizophrenia or schizoaffective disorder","volume":"143","author":"Eisen JL","year":"1997","journal-title":"Am J Psychiatry"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.12.1.16"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.5.1002"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1819.2003.01081.x"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3956(99)00048-5"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-9338(01)00590-9"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-9964(01)00373-5"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1614.1998.00374.x"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0010-440X(91)90025-8"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.157.3.430"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.schbul.a033472"},{"key":"e_1_2_7_16_2","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1176\/ajp.156.3.474","article-title":"Multiple anxiety disorder comorbidity in patients with mood spectrum disorders with psychotic features","volume":"156","author":"Cassano GB","year":"1999","journal-title":"Am J Psychiatry"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.152.5.755"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.161.1.53"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2004.07.009"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.3928\/0048-5713-19930701-11"},{"key":"e_1_2_7_21_2","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1176\/jnp.14.4.449","article-title":"Association of obsessions and compulsions in schizophrenia with neurocognition and negative symptoms","volume":"14","author":"Lysaker PH","year":"2002","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"e_1_2_7_22_2","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1017\/S1092852900004715","article-title":"Are schizophrenia and OCD related disorders?","volume":"2","author":"Mcglashan TH","year":"1997","journal-title":"CNS Spectr"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852900004612"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1614.2004.01487.x"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.143.4.437"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2005.09.016"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1781(01)00238-4"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1521\/psyc.64.4.319.18602"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.185.3.220"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.schbul.a007067"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1300\/J229v07n03_02"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v66n1010"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.nmd.0000188970.11916.76"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.nmd.0000172480.56308.21"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1176\/ps.50.11.1467"},{"key":"e_1_2_7_36_2","first-page":"489","article-title":"Childhood abuse and positive symptoms of schizophrenia","volume":"45","author":"Ross CA","year":"1994","journal-title":"Hosp Comm Psychiatry"},{"key":"e_1_2_7_37_2","first-page":"587","article-title":"Childhood risk factors in dually diagnosed homeless adults","volume":"38","author":"Blankertz LE","year":"1993","journal-title":"Soc Work"},{"key":"e_1_2_7_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/jts.20114"},{"key":"e_1_2_7_39_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.55.2.157"},{"key":"e_1_2_7_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/23.4.685"},{"key":"e_1_2_7_41_2","doi-asserted-by":"publisher","DOI":"10.1023\/B:JOTS.0000048957.70768.b9"},{"key":"e_1_2_7_42_2","volume-title":"Structured clinical interview for DSM IV","author":"First M","year":"1997"},{"key":"e_1_2_7_43_2","volume-title":"Multidimensional anxiety questionnaire. Lutz","author":"Reynolds WM","year":"1999"},{"key":"e_1_2_7_44_2","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/13.2.261"},{"key":"e_1_2_7_45_2","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/10.3.388"},{"key":"e_1_2_7_46_2","doi-asserted-by":"publisher","DOI":"10.1037\/h0037562"},{"key":"e_1_2_7_47_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-003-0660-1"},{"key":"e_1_2_7_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13310-7"},{"key":"e_1_2_7_49_2","doi-asserted-by":"publisher","DOI":"10.1080\/13854049108403297"},{"key":"e_1_2_7_50_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1976.01770040068012"},{"key":"e_1_2_7_51_2","volume-title":"Multivariate analysis: methods and applications","author":"Dillon WR","year":"1984"},{"key":"e_1_2_7_52_2","unstructured":"SPSS Inc.spss Base 10.0 User\u2019s Guide. Chicago IL:SPSS Inc. 1999."},{"key":"e_1_2_7_53_2","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-2-13"},{"key":"e_1_2_7_54_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.psych.48.1.449"},{"key":"e_1_2_7_55_2","author":"Foa EB","year":"2000","journal-title":"Effective treatments for PTSD: guidelines from the International Society for Traumatic Stress Studies"},{"key":"e_1_2_7_56_2","doi-asserted-by":"publisher","DOI":"10.1080\/09638230500066356"},{"key":"e_1_2_7_57_2","doi-asserted-by":"publisher","DOI":"10.1080\/15487760490476200"},{"key":"e_1_2_7_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2004.01.007"},{"key":"e_1_2_7_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-9964(02)00316-X"}],"container-title":["Acta Psychiatrica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0447.2007.01067.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0447.2007.01067.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T11:03:42Z","timestamp":1697454222000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0447.2007.01067.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,24]]},"references-count":58,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["10.1111\/j.1600-0447.2007.01067.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0447.2007.01067.x","archive":["Portico"],"relation":{},"ISSN":["0001-690X","1600-0447"],"issn-type":[{"value":"0001-690X","type":"print"},{"value":"1600-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8,24]]}}}