{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:26:40Z","timestamp":1791070000128,"version":"4.1.0"},"reference-count":48,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2009,2,15]],"date-time":"2009-02-15T00:00:00Z","timestamp":1234656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:p><jats:bold>Objective:\u2002<\/jats:bold> We explored the subjective effects associated with olanzapine, risperidone and older antipsychotics.<\/jats:p><jats:p><jats:bold>Method:\u2002<\/jats:bold> We conducted a content analysis of an Internet database of comments about prescribed medications.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> We analysed 223 comments on risperidone, 170 on olanzapine and 46 relating to three older antipsychotics. The predominant subjective effects produced by all drugs consisted of sedation, cognitive impairment and emotional flattening or indifference. Connections appeared between these effects and Parkinsonian\u2010like symptoms with the older drugs, sexual impairment with risperidone and metabolic effects with olanzapine. The experience of akathisia was frequently linked to suicidal thoughts. Some respondents described how the drugs\u2019 subjective effects helped to reduce symptoms of mania, psychosis and anxiety.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> The generalisability of Internet data is uncertain. 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