{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T02:53:32Z","timestamp":1782269612125,"version":"3.54.5"},"reference-count":67,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,11,19]],"date-time":"2011-11-19T00:00:00Z","timestamp":1321660800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>Goldstein MR, Plante DT, Hulse BK, Sarasso S, Landsness EC, Tononi G, Benca RM. Overnight changes in waking auditory evoked potential amplitude reflect altered sleep homeostasis in major depression.<\/jats:p><jats:p><jats:bold>Objective:\u2002<\/jats:bold> Sleep homeostasis is altered in major depressive disorder (MDD). Pre\u2010 to postsleep decline in waking auditory evoked potential (AEP) amplitude has been correlated with sleep slow wave activity (SWA), suggesting that overnight changes in waking AEP amplitude are homeostatically regulated in healthy individuals. This study investigated whether the overnight change in waking AEP amplitude and its relation to SWA is altered in MDD.<\/jats:p><jats:p><jats:bold>Method:\u2002<\/jats:bold> Using 256\u2010channel high\u2010density electroencephalography, all\u2010night sleep polysomnography and single\u2010tone waking AEPs pre\u2010 and postsleep were collected in 15 healthy controls (HC) and 15 non\u2010medicated individuals with MDD.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> N1 and P2 amplitudes of the waking AEP declined after sleep in the HC group, but not in MDD. The reduction in N1 amplitude also correlated with fronto\u2010central SWA in the HC group, but a comparable relationship was not found in MDD, despite equivalent SWA between groups. No pre\u2010 to postsleep differences were found for N1 or P2 latencies in either group. These findings were not confounded by varying levels of alertness or differences in sleep variables between groups.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> MDD involves altered sleep homeostasis as measured by the overnight change in waking AEP amplitude. Future research is required to determine the clinical implications of these findings.<\/jats:p>","DOI":"10.1111\/j.1600-0447.2011.01796.x","type":"journal-article","created":{"date-parts":[[2011,11,19]],"date-time":"2011-11-19T05:19:52Z","timestamp":1321679992000},"page":"468-477","source":"Crossref","is-referenced-by-count":25,"title":["Overnight changes in waking auditory evoked potential amplitude reflect altered sleep homeostasis in major depression"],"prefix":"10.1111","volume":"125","author":[{"given":"M. R.","family":"Goldstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. T.","family":"Plante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. K.","family":"Hulse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Sarasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. C.","family":"Landsness","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Tononi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M.","family":"Benca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,11,19]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1992.01820080059010"},{"key":"e_1_2_9_3_2","volume-title":"Diagnostic and statistical manual of mental disorders: DSM\u2010IV\u2010TR","author":"American Psychiatric Association, American Psychiatric Association Task Force on DSM\u2010IV","year":"2000"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2009.08.013"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1988.01800310088011"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)92090-9"},{"key":"e_1_2_9_7_2","first-page":"195","article-title":"A two process model of sleep regulation","volume":"1","author":"Borb\u00e9ly AA","year":"1982","journal-title":"Hum Neurobiol"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(93)90016-5"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2005.05.002"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2009.08.024"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1017069"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2007.00968.x"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-011-0195-5"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2011.01.041"},{"key":"e_1_2_9_15_2","volume-title":"Structured clinical interview for DSM\u2010IV\u2010TR axis I disorders, research version, patient edition","author":"First M","year":"2002"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8341.1959.tb00467.x"},{"key":"e_1_2_9_17_2","volume-title":"Structured clinical interview for DSM\u2010IV\u2010TR axis I disorders, research version, non\u2010patient edition (SCID\u2010I\/NP)","author":"First M","year":"2002"},{"key":"e_1_2_9_18_2","first-page":"267","article-title":"Cumulative sleepiness, mood disturbance, and psychomotor vigilance performance decrements during a week of sleep restricted to 4\u20135\u2003hours per night","volume":"20","author":"Dinges D","year":"1997","journal-title":"Sleep"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/32.10.1273"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.1053\/smrv.2000.0098"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(03)00093-2"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-7634(01)00027-6"},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbp003"},{"key":"e_1_2_9_24_2","volume-title":"New handbook of auditory evoked responses","author":"Hall J","year":"1992"},{"key":"e_1_2_9_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01616744"},{"key":"e_1_2_9_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(80)90419-8"},{"key":"e_1_2_9_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2005.11.003"},{"key":"e_1_2_9_28_2","volume-title":"The AAASM manual for the scoring of sleep and associated events: rules, terminology, and technical specifications","author":"Iber C","year":"2007"},{"key":"e_1_2_9_29_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.1058"},{"key":"e_1_2_9_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(76)90177-2"},{"key":"e_1_2_9_31_2","doi-asserted-by":"publisher","DOI":"10.1080\/00207450600773509"},{"key":"e_1_2_9_32_2","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0b013e3181dc1bad"},{"key":"e_1_2_9_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(02)00146-3"},{"key":"e_1_2_9_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1987.tb00311.x"},{"key":"e_1_2_9_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2003.11.021"},{"key":"e_1_2_9_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(99)00074-3"},{"key":"e_1_2_9_37_2","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.105.091199"},{"key":"e_1_2_9_38_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004060050024"},{"key":"e_1_2_9_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1781(00)00178-5"},{"key":"e_1_2_9_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(81)90023-8"},{"key":"e_1_2_9_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00016-2"},{"key":"e_1_2_9_42_2","doi-asserted-by":"publisher","DOI":"10.1111\/1469-8986.3510054"},{"key":"e_1_2_9_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2009.08.010"},{"key":"e_1_2_9_44_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2869.2003.00357.x"},{"key":"e_1_2_9_45_2","doi-asserted-by":"publisher","DOI":"10.2174\/157015908787386050"},{"key":"e_1_2_9_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(80)90093-2"},{"key":"e_1_2_9_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(87)90067-9"},{"key":"e_1_2_9_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(92)90019-Y"},{"key":"e_1_2_9_49_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/23.5.1c"},{"key":"e_1_2_9_50_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003446-200104000-00001"},{"key":"e_1_2_9_51_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2005.04293.x"},{"key":"e_1_2_9_52_2","first-page":"343","volume-title":"Plasticity and signal representation in the auditory system","author":"Roberts L","year":"2005"},{"key":"e_1_2_9_53_2","first-page":"251","article-title":"Induction of LTP\u2010like changes in human auditory cortex by rapid auditory stimulation: an FMRI study","volume":"25","author":"Zaehle T","year":"2007","journal-title":"Restor Neurol Neurosci"},{"key":"e_1_2_9_54_2","doi-asserted-by":"publisher","DOI":"10.1162\/jocn.2008.20157"},{"key":"e_1_2_9_55_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000276"},{"key":"e_1_2_9_56_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2009.06720.x"},{"key":"e_1_2_9_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1629"},{"key":"e_1_2_9_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2006.10.006"},{"key":"e_1_2_9_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2010.05.026"},{"key":"e_1_2_9_60_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2011.01744.x"},{"key":"e_1_2_9_61_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700007856"},{"key":"e_1_2_9_62_2","doi-asserted-by":"publisher","DOI":"10.1586\/ern.10.83"},{"key":"e_1_2_9_63_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2011.02.003"},{"key":"e_1_2_9_64_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(88)90162-X"},{"key":"e_1_2_9_65_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1014281"},{"key":"e_1_2_9_66_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130050070"},{"key":"e_1_2_9_67_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v68n0806"},{"key":"e_1_2_9_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2006.07.021"}],"container-title":["Acta Psychiatrica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0447.2011.01796.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0447.2011.01796.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T16:55:08Z","timestamp":1698771308000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0447.2011.01796.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11,19]]},"references-count":67,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1111\/j.1600-0447.2011.01796.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0447.2011.01796.x","archive":["Portico"],"relation":{},"ISSN":["0001-690X","1600-0447"],"issn-type":[{"value":"0001-690X","type":"print"},{"value":"1600-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,11,19]]}}}