{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T19:53:22Z","timestamp":1760385202566},"reference-count":48,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,2,9]],"date-time":"2012-02-09T00:00:00Z","timestamp":1328745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p>Murru A, Pacchiarotti I, Nivoli AMA, Bonnin CM, Patrizi B, Amann B, Vieta E, Colom F. Rates and clinical correlates of treatment non\u2010adherence in schizoaffective bipolar patients.<\/jats:p><jats:p><jats:bold>Objective:\u2002<\/jats:bold> To analyze demographical, clinical, and therapeutic variables that may be associated with pharmacological non\u2010adherence in a sample of schizoaffective patients, bipolar type.<\/jats:p><jats:p><jats:bold>Method:\u2002<\/jats:bold> Adherence to treatment and its clinical correlates were assessed at the end of a 10\u2010year follow\u2010up in 76 patients meeting DSM\u2010IV\u2010TR diagnosis of schizoaffective disorder, bipolar type. Adherent and poorly adherent patients were compared regarding clinical and therapeutic variables.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> The rate of poorly adherent patients was 32\/76 (41.2%) of the sample. Adherent patients were more likely to have presented an affective episode at illness onset and to have fewer purely \u2013 non\u2010affective \u2013 psychotic episodes. Demographic or other clinical variables were not found to be associated to treatment adherence. Family history for psychiatric disorders or suicide did not correlate either, and neither did any specific pharmacological agent.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Rates of non\u2010adherence in schizoaffective disorder are high. Adherence seems to be associated to a more affective course of illness (affective first episode and fewer purely psychotic episodes). Patients with more prominent schizophrenia\u2010like characteristics could be at higher risk for poor adherence and need to be closely followed and monitored. Even when properly treated, schizoaffective disorder is a disabling and severe disorder with high risk for recurrences.<\/jats:p>","DOI":"10.1111\/j.1600-0447.2012.01837.x","type":"journal-article","created":{"date-parts":[[2012,2,9]],"date-time":"2012-02-09T23:18:36Z","timestamp":1328829516000},"page":"412-418","source":"Crossref","is-referenced-by-count":15,"title":["Rates and clinical correlates of treatment non\u2010adherence in schizoaffective bipolar patients"],"prefix":"10.1111","volume":"125","author":[{"given":"A.","family":"Murru","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Pacchiarotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M. A.","family":"Nivoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. M.","family":"Bonnin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Patrizi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Amann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Vieta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Colom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,2,9]]},"reference":[{"key":"e_1_2_9_2_2","first-page":"98","volume-title":"American Psychiatric Association Annual Review","author":"Docherty JP","year":"1986"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v61n0802"},{"key":"e_1_2_9_4_2","first-page":"292","article-title":"Factors associated with pharmacologic noncompliance in patients with mania","volume":"57","author":"Keck PE","year":"1996","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.psc.2007.04.002"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v68n0601"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.10.1653"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0447.2002.1e003.x"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890423349"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-9338(01)00559-4"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1176\/ps.46.12.1254"},{"key":"e_1_2_9_12_2","first-page":"CD000011","article-title":"Interventions for helping patients to follow prescriptions for medications","volume":"2","author":"Haynes RB","year":"2001","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04221"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-9964(97)00131-X"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7176.2008.07572.x"},{"issue":"21","key":"e_1_2_9_16_2","first-page":"25","article-title":"Adherence to antipsychotic medications","volume":"60","author":"Perkins DO","year":"1999","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.9096su1cc.03"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2009.01424.x"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2004.00160.x"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v63n1206"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1995.03950150005001"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1159\/000012361"},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3956(98)00024-7"},{"key":"e_1_2_9_24_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04408"},{"key":"e_1_2_9_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2007.01072.x"},{"key":"e_1_2_9_26_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.108.055731"},{"key":"e_1_2_9_27_2","first-page":"230","article-title":"Executive dysfunction and memory impairment in schizoaffective disorder: a comparison with bipolar disorder, schizophrenia and healthy controls","volume":"52","author":"Amann B","year":"2000","journal-title":"Psychol Med"},{"key":"e_1_2_9_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2006.00368.x"},{"key":"e_1_2_9_29_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2005.00248.x"},{"issue":"1","key":"e_1_2_9_30_2","first-page":"24","article-title":"Improving treatment adherence in bipolar disorder through psychoeducation","volume":"66","author":"Vieta E","year":"2005","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_9_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2010.11.017"},{"key":"e_1_2_9_32_2","doi-asserted-by":"publisher","DOI":"10.3371\/CSRP.4.3.3"},{"key":"e_1_2_9_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rpsm.2011.01.002"},{"key":"e_1_2_9_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.2051-5545.2011.tb00037.x"},{"key":"e_1_2_9_35_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.23.1.56"},{"key":"e_1_2_9_36_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.133.5.429"},{"key":"e_1_2_9_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/13.2.261"},{"key":"e_1_2_9_38_2","doi-asserted-by":"publisher","DOI":"10.3371\/CSRP.4.1.6"},{"key":"e_1_2_9_39_2","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbj075"},{"key":"e_1_2_9_40_2","doi-asserted-by":"publisher","DOI":"10.1080\/10673220701650383"},{"key":"e_1_2_9_41_2","first-page":"366","article-title":"All source verification: a new tool for measuring adherence in schizophrenia","volume":"35","author":"Schooler NR","year":"2009","journal-title":"Schizophr Bull"},{"key":"e_1_2_9_42_2","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1176\/ps.2009.60.2.210","article-title":"Treatment patterns for schizoaffective disorder and schizophrenia among Medicaid patients","volume":"60","author":"Olfson M","year":"2009","journal-title":"Psychiatr Serv"},{"key":"e_1_2_9_43_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v69n0114"},{"key":"e_1_2_9_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-9964(01)00312-7"},{"key":"e_1_2_9_45_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0447.108.s418.7.x"},{"key":"e_1_2_9_46_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.9.904"},{"key":"e_1_2_9_47_2","doi-asserted-by":"publisher","DOI":"10.1331\/154434503322642598"},{"key":"e_1_2_9_48_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v67n0715"},{"key":"e_1_2_9_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2011.03.001"}],"container-title":["Acta Psychiatrica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0447.2012.01837.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0447.2012.01837.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T22:14:45Z","timestamp":1697408085000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0447.2012.01837.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,9]]},"references-count":48,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["10.1111\/j.1600-0447.2012.01837.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0447.2012.01837.x","archive":["Portico"],"relation":{},"ISSN":["0001-690X","1600-0447"],"issn-type":[{"value":"0001-690X","type":"print"},{"value":"1600-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,2,9]]}}}