{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T17:36:58Z","timestamp":1774633018659,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,5,24]],"date-time":"2006-05-24T00:00:00Z","timestamp":1148428800000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2006,5]]},"abstract":"<jats:p>Xanthogranulomatous inflammation is rare, mainly involving the kidneys, while primary xanthogranulomatous endometritis (XE) is a very unusual finding, histologically characterized by partial or complete replacement of the mucosa by granulation tissue with an abundance of foamy histiocytes, siderophages and multinucleated giant cells. We present the case of a 69\u2010year\u2010old woman with a short history of abdominal pain and a palpable mass in the pouch of Douglas. Dilatation of the cervix drained a pyometra. Histological examination of the curettage rendered the diagnosis of XE. Microbiological studies revealed enterococcus spp. and <jats:italic>Peptostreptococcus magnus.<\/jats:italic> Despite antibiotic treatment the patient died of heart failure due to systemic inflammation. Autopsy confirmed the diagnosis of XE with transmural extension into the peritoneal cavity. Such a lethal course of XE is extraordinary. Proposed causes of XE include obstruction, infection and hemorrhage. Demonstration of enterococcus spp. and <jats:italic>P. magnus<\/jats:italic> supports the probable significance of bacteria in the development of XE. Because this condition may mimic malignant disease macroscopically and histologically, knowledge of XE is of major importance for both pathologists and gynecologists.<\/jats:p>","DOI":"10.1111\/j.1600-0463.2006.apm_281.x","type":"journal-article","created":{"date-parts":[[2006,5,24]],"date-time":"2006-05-24T13:02:44Z","timestamp":1148475764000},"page":"386-388","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Lethal outcome in xanthogranulomatous endometritis"],"prefix":"10.1111","volume":"114","author":[{"given":"FRANK","family":"NOACK","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JULIANE","family":"BRIESE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"FLORIAN","family":"STELLMACHER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DANIELA","family":"HORNUNG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HANS\u2010PETER","family":"HORNY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,5,24]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197903000-00005"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198110000-00007"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1988.tb02078.x"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-200204000-00006"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1980.tb02902.x"},{"key":"e_1_2_4_7_2","first-page":"281","article-title":"Pseudoxanthomat\u00f6se Endometritis","volume":"110","author":"Kohn R","year":"1967","journal-title":"Zentralb Allg Pathol"},{"key":"e_1_2_4_8_2","volume-title":"Blaustein's Pathology of the Female Genital Tract","author":"Sherman M","year":"2002"},{"key":"e_1_2_4_9_2","first-page":"273","article-title":"Xanthomatous endometritis","volume":"7","author":"Blanco C","year":"1989","journal-title":"Appl Pathol"},{"key":"e_1_2_4_10_2","first-page":"239","article-title":"Spontaneously resolved female infertility associated with histiocytic endometritis","volume":"18","author":"Moukassa D","year":"1998","journal-title":"Ann Pathol"},{"key":"e_1_2_4_11_2","first-page":"929","article-title":"Xanthogranulomatous endometritis. 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