{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:49:06Z","timestamp":1759009746492},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,2,23]],"date-time":"2006-02-23T00:00:00Z","timestamp":1140652800000},"content-version":"vor","delay-in-days":53,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:p>In the present study, 10 azithromycin\u2010resistant <jats:italic>Neisseria gonorrhoeae<\/jats:italic> isolates from 6 Swedish male patients in 2004, 3 sporadic Swedish azithromycin\u2010resistant <jats:italic>N. gonorrhoeae<\/jats:italic> isolates from recent years and one Swedish <jats:italic>N. gonorrhoeae<\/jats:italic> isolate from 2003 that was susceptible to azithromycin but assigned the same serological variant (serovar), i.e. IB\u201037, as the isolates from 2004 were included. The isolates were characterized phenotypically using antibiograms and serovar determination and genetically with pulsed\u2010field gel electrophoresis (PFGE), entire <jats:italic>porB<\/jats:italic> gene sequencing and <jats:italic>N. gonorrhoeae<\/jats:italic> multiantigen sequence typing (NG\u2010MAST). The epidemiological information and the results of the thorough phenotypic characterisation and genetic characterisation identified the first presumed domestic transmission of one azithromycin\u2010resistant <jats:italic>N. gonorrhoeae<\/jats:italic> strain in Sweden in 2004. This stresses the need for continuous surveillance of the antibiotic susceptibility of <jats:italic>N. gonorrhoeae<\/jats:italic> in order to identify emergence of new resistance, monitor the changing patterns of the susceptibility, and be able to update treatment recommendations on a regular basis.<\/jats:p>","DOI":"10.1111\/j.1600-0463.2006.apm_332.x","type":"journal-article","created":{"date-parts":[[2006,2,23]],"date-time":"2006-02-23T16:53:40Z","timestamp":1140713620000},"page":"67-71","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Molecular epidemiology of <i>Neisseria gonorrhoeae<\/i>\u2013 identification of the first presumed Swedish transmission chain of an azithromycin\u2010resistant strain"],"prefix":"10.1111","volume":"114","author":[{"given":"DAVID","family":"LUNDB\u00c4CK","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HANS","family":"FREDLUND","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TORSTEN","family":"BERGLUND","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BENGT","family":"WRETLIND","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MAGNUS","family":"UNEMO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,2,23]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2004.009415"},{"key":"e_1_2_6_3_2","unstructured":"TapsallJ.Antimicrobial resistance inNeisseria gonorrhoeae.World Health Organization (WHO) report2001;WHOCDSCSRDSR2001.3."},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1258\/0956462021924730"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-200109000-00006"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-200305000-00012"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkg040"},{"key":"e_1_2_6_8_2","unstructured":"SWEDRES2004.A Report on Swedish Antibiotic Utilisation and Resistance in Human Medicine. 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