{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:05:36Z","timestamp":1791266736322,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2010,1,24]],"date-time":"2010-01-24T00:00:00Z","timestamp":1264291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:p>Gradel KO, N\u00f8rgaard M, Sch\u00f8nheyder HC, Dethlefsen C, Ejlertsen T, Kristensen B, Nielsen H. <jats:italic>Salmonella<\/jats:italic> or <jats:italic>Campylobacter<\/jats:italic> gastroenteritis prior to a cancer diagnosis does not aggravate the prognosis: a population\u2010based follow\u2010up study. APMIS 2010; 118: 136\u201342.<\/jats:p><jats:p>We hypothesized that preceding zoonotic <jats:italic>Salmonella<\/jats:italic> or <jats:italic>Campylobacter<\/jats:italic> gastroenteritis aggravated the prognosis in cancer patients. Exposed patients comprised all of those diagnosed with first\u2010time <jats:italic>Salmonella<\/jats:italic>\/<jats:italic>Campylobacter<\/jats:italic> gastroenteritis from 1991 and with first\u2010time cancer diagnosis thereafter (through 2003) in two Danish counties. These patients were matched for main cancer type, gender, age and calendar period to unexposed cancer patients, i.e. those without <jats:italic>Salmonella<\/jats:italic>\/<jats:italic>Campylobacter<\/jats:italic> gastroenteritis. We compared cancer stage by age\u2010 and comorbidity\u2010adjusted logistic regression analysis, survival by comorbidity\u2010adjusted Cox\u2019s regression analysis and mortality dependent on the time period between <jats:italic>Salmonella<\/jats:italic>\/<jats:italic>Campylobacter<\/jats:italic> gastroenteritis and cancer by spline regression curves. The study cohort comprised 272 <jats:italic>Salmonella<\/jats:italic>\/<jats:italic>Campylobacter<\/jats:italic>\u2010exposed cancer patients and 2681 unexposed cancer patients. Prevalence odds ratios [95% confidence intervals (CI)] in exposed as compared with unexposed patients were 0.96 (0.74\u20131.25) for localized tumours, 1.15 (0.87\u20131.54) for regional spread and 1.14 (0.84\u20131.55) for metastases. Adjusted mortality rate ratios (95% CI) were 0.93 (0.75\u20131.16) for 0\u20131\u2003year, 1.08 (0.84\u20131.39) for 2\u20135\u2003years and 1.02 (0.60\u20131.73) for the remaining period. Mortality estimates did not change in relation to the time period between gastroenteritis and cancer. <jats:italic>Salmonella<\/jats:italic>\/<jats:italic>Campylobacter<\/jats:italic> gastroenteritis prior to cancer was associated with neither the cancer stage nor a poorer prognosis.<\/jats:p>","DOI":"10.1111\/j.1600-0463.2009.02571.x","type":"journal-article","created":{"date-parts":[[2010,1,24]],"date-time":"2010-01-24T13:43:42Z","timestamp":1264340622000},"page":"136-142","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<i>Salmonella<\/i> or <i>Campylobacter<\/i> gastroenteritis prior to a cancer diagnosis does not aggravate the prognosis: a population\u2010based follow\u2010up study"],"prefix":"10.1111","volume":"118","author":[{"given":"KIM O.","family":"GRADEL","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"METTE","family":"N\u00d8RGAARD","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HENRIK C.","family":"SCH\u00d8NHEYDER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CLAUS","family":"DETHLEFSEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TOVE","family":"EJLERTSEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BRIAN","family":"KRISTENSEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HENRIK","family":"NIELSEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,1,24]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.318.7190.1046"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/381578"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268807009314"},{"key":"e_1_2_6_5_2","volume-title":"Salmonella Enterica Serovar Enteritidis in Humans and Animals \u2013 Epidemiology, Pathogenesis, and Control","author":"Saeed AM","year":"1999"},{"key":"e_1_2_6_6_2","first-page":"598","article-title":"Incidence of campylobacteriosis among patients with AIDS in Los Angeles County","volume":"4","author":"Sorvillo FJ","year":"1991","journal-title":"J Acquir Immune Defic Syndr"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/18.3.358"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1086\/520681"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7385.357"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1202.050867"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365540801961248"},{"key":"e_1_2_6_12_2","unstructured":"Danmarks Statistik.Population Statistics Denmark.http:\/\/www.statistikbanken.dk(accessed on 10 December 2009)."},{"key":"e_1_2_6_13_2","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1128\/JCM.37.7.2312-2316.1999","article-title":"Evaluation of Statens Serum Institut enteric medium for detection of enteric pathogens","volume":"37","author":"Blom M","year":"1999","journal-title":"J Clin Microbiol"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.1.286-291.2000"},{"key":"e_1_2_6_15_2","volume-title":"Antigenic Formulas of the Salmonella Serovars","author":"Popoff MY","year":"1997"},{"key":"e_1_2_6_16_2","first-page":"441","article-title":"The Danish Civil Registration System. 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