{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T16:12:15Z","timestamp":1776269535163,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2010,8,17]],"date-time":"2010-08-17T00:00:00Z","timestamp":1282003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:p>Park SD, Uh Y, Lee G, Lim K, Kim JB, Jeong SH. Prevalence and resistance patterns of extended\u2010spectrum and AmpC \u03b2\u2010lactamase in <jats:italic>Escherichia coli<\/jats:italic>, <jats:italic>Klebsiella pneumoniae<\/jats:italic>, <jats:italic>Proteus mirabilis,<\/jats:italic> and <jats:italic>Salmonella<\/jats:italic> serovar Stanley in a Korean tertiary hospital. APMIS 2010; 118: 801\u20138.<\/jats:p><jats:p>A total of 100 clinical isolates of <jats:italic>Escherichia coli<\/jats:italic> (n\u2003=\u200335)<jats:italic>, Klebsiella pneumoniae<\/jats:italic> (n\u2003=\u200363)<jats:italic>, Proteus mirabilis<\/jats:italic> (n\u2003=\u20031), and Salmonella serovar Stanley (n\u2003=\u20031), showing resistance to cefoxitin, or returning positive in extended\u2010spectrum \u03b2\u2010lactamase (ESBL) by Clinical and Laboratory Standards Institute (CLSI) ESBL confirmatory method, were studied. The isolates were examined by the boronic acid (BA) disk test, polymerase chain reaction, and pulsed\u2010field gel electrophoresis (PFGE) to investigate genetic similarities. The concurrence rates for ESBLs by the CLSI and the BA disk test were 97% for <jats:italic>E. coli<\/jats:italic> and 96.7% for <jats:italic>K. pneumoniae<\/jats:italic>. A total of 41 isolates showing cefoxitin resistance yielded all positive by the BA disk test. All the 33 <jats:italic>K. pneumoniae<\/jats:italic> isolates, which showed positive by the BA disk test, were carrying AmpC genes. The TEM and CTX\u2010M types were predominant in <jats:italic>E. coli<\/jats:italic> and the SHV and the CIT and\/or DHA types were predominant in <jats:italic>K. pneumoniae<\/jats:italic>. PFGE analysis showed almost 75% of genetic similarities among <jats:italic>K. pneumoniae<\/jats:italic> isolates producing ESBLs and\/or AmpC \u03b2\u2010lactamases (AmpCs) as each <jats:italic>K. pneumoniae<\/jats:italic> carried variable genes and showed variable antibiotic patterns. Clearly, the BA disk test was a useful method for the detection of ESBLs and AmpCs. In particular, cefoxitin resistance and BA\u2010positive trait of <jats:italic>K. pneumoniae<\/jats:italic> do reflect the presence of AmpC genes in the organism.<\/jats:p>","DOI":"10.1111\/j.1600-0463.2010.02663.x","type":"journal-article","created":{"date-parts":[[2010,8,17]],"date-time":"2010-08-17T21:37:17Z","timestamp":1282081037000},"page":"801-808","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Prevalence and resistance patterns of extended\u2010spectrum and AmpC \u03b2\u2010lactamase in <i>Escherichia coli<\/i>, <i>Klebsiella pneumoniae<\/i>, <i>Proteus mirabilis,<\/i> and <i>Salmonella<\/i> serovar Stanley in a Korean tertiary hospital"],"prefix":"10.1111","volume":"118","author":[{"given":"SOON DEOK","family":"PARK","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YOUNG","family":"UH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GYUSANG","family":"LEE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KWANHUN","family":"LIM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JONG BAE","family":"KIM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SEOK HOON","family":"JEONG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,8,17]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008991724288"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1201-9712(98)90090-X"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.7.2902-2906.2004"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2006.12.44"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2006.01.012"},{"key":"e_1_2_5_7_2","unstructured":"Clinical and Laboratory Standards Institute.Performance standards for antimicrobial susceptibility testing: 16th informational supplement. 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