{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:42:18Z","timestamp":1790023338488,"version":"4.0.1"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,6,4]],"date-time":"2004-06-04T00:00:00Z","timestamp":1086307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2004,8]]},"abstract":"<jats:p><jats:bold>Abstract: <\/jats:bold> Guided bone regeneration is a predictable and well\u2010documented surgical approach for the treatment of deficient alveolar ridges prior to endosseous implant placement. The purpose of this study was to compare a new resorbable membrane (GORE RESOLUT ADAPT Regenerative Membrane, i.e. 67% glycolide (PGA)\u2003:\u200333% trimethyline carbonate (TMC)) with Bio\u2010Gide<jats:sup>\u00ae<\/jats:sup>, a resorbable collagen membrane. Five canines were used in the study. Three saddle\u2010type osseous defects were created bilaterally in edentulous areas of the mandible. The defects were filled with assayed, canine demineralized freeze\u2010dried bone (DFDB) in a thermoplastic gelatin matrix. Using a randomized block design, four sites were covered with PGA\u2003:\u2003TMC membranes of four different porosities, one site was covered with a collagen membrane and one site consisted of DFDB alone (control). At 3 months, the animals were euthanized and the mandibles were removed <jats:italic>en bloc<\/jats:italic> for laboratory processing. A total of 30 sites were reviewed microradiographically and underwent histomorphometric analysis for bone regeneration, soft tissue presence and remaining graft material. All sites exhibited uneventful healing. A significantly higher percentage of bone regeneration was seen in the sites protected by the PGA\u2003:\u2003TMC membrane. A higher component of soft tissue was visible beneath the collagen membrane as compared with the PGA\u2003:\u2003TMC membrane. The control sites exhibited noticeable deformation of the regenerated bone secondary to collapse of the overlying periosteum. The authors conclude that the PGA\u2003:\u2003TMC membrane protected the DFDB\u2010filled defect and allowed a greater amount of bone regeneration than the defect protected by the collagen membrane or the control.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2004.01029.x","type":"journal-article","created":{"date-parts":[[2004,7,9]],"date-time":"2004-07-09T14:52:59Z","timestamp":1089384779000},"page":"435-442","source":"Crossref","is-referenced-by-count":65,"title":["A comparative study of barrier membranes as graft protectors in the treatment of localized bone defects"],"prefix":"10.1111","volume":"15","author":[{"given":"Franci","family":"Stavropoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christer","family":"Dahlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D.","family":"Ruskin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Johansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,9,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2001.012003260.x"},{"key":"e_1_2_10_3_1","first-page":"377","article-title":"Guided tissue regeneration for implants placed into extraction sockets and for implant dehiscences","volume":"10","author":"Becker W.","year":"1990","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_10_4_1","first-page":"31","article-title":"The use of e\u2010PTFE barrier membranes for bone promotion around titanium implants placed into extraction sockets","volume":"9","author":"Becker W.","year":"1994","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070212.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1998.090301.x"},{"key":"e_1_2_10_7_1","first-page":"666","article-title":"Osseointegration of titanium implants in bone regenerated in membrane\u2010protected defects","volume":"10","author":"Buser D.","year":"1995","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1991.74.3.0487"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/02844319009004514"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198805000-00004"},{"key":"e_1_2_10_11_1","first-page":"318","article-title":"Die Trenn\u2010D\u00fcnnscliff\u2010Technik zur Herstellung histologischer Pr\u00e4paraten von nicht schneidbaren Geweben und Materialen","volume":"34","author":"Donath K.","year":"1988","journal-title":"Der Pr\u00e4parator"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1982.tb00172.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1995.66.4.303"},{"key":"e_1_2_10_14_1","first-page":"101","volume-title":"Guided bone regeneration in implant dentistry","author":"Hardwick R.","year":"1994"},{"key":"e_1_2_10_15_1","unstructured":"Johansson C.B.(1991) On tissue reaction to metal implants. 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