{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T20:26:52Z","timestamp":1793824012710,"version":"4.6.1"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,2,9]],"date-time":"2005-02-09T00:00:00Z","timestamp":1107907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2005,6]]},"abstract":"<jats:p><jats:bold>Abstract: <\/jats:bold> One of the key factors for attaining osseointegration is the presence of an adequate osseous volume. In patients with inadequate osseous width or height, a bone augmentation using the guided bone regeneration (GBR) concept may be applied either with a simultaneous or a staged approach. The aim of this multicenter prospective case series study was to evaluate the efficacy and predictability of the GBR technique (simultaneous approach) in patients with peri\u2010implant osseous defects, both dehiscences and fenestrations. Results 5 years post\u2010treatment (survival rates and marginal bone level) were assessed. A total of 19 consecutive patients with 26 peri\u2010implant osseous defects (20 dehiscences and six fenestrations) were treated during the period from September 1992 to June 1993 with a simultaneous GBR approach using non\u2010resorbable membranes combined with autogenous bone grafts or decalcified freeze\u2010dried bone allograft. The mean osseous augmentation was 94.8%. Marginal bone levels at re\u2010entry and 5 years after surgery were calculated from standardized periapical radiographs. One implant was lost 3 months after loading. Thus, the cumulative survival rate was 96.1% after 5 years. The mean marginal bone level after 5 years was 2.03\u2003mm (SD=\u00b10.5), without a difference between mesial and distal sites. This study demonstrates that implants with peri\u2010implant defects that are treated with GBR had similar survival rates and crestal bone levels compared with implants in native bone.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2005.01106.x","type":"journal-article","created":{"date-parts":[[2005,5,6]],"date-time":"2005-05-06T08:45:08Z","timestamp":1115369108000},"page":"294-301","source":"Crossref","is-referenced-by-count":86,"title":["Long\u2010term results and survival rate of implants treated with guided bone regeneration: a 5\u2010year case series prospective study"],"prefix":"10.1111","volume":"16","author":[{"given":"Juan","family":"Blanco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel","family":"Alonso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano","family":"Sanz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,2,9]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"347","article-title":"A long\u2010term follow\u2010up study of osseointegrated implants in the treatment of totally edentulous jaws","volume":"5","author":"Adell R.","year":"1990","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_3_1","first-page":"211","volume-title":"Tissue\u2010integrated Prostheses: Osseointegration in Clinical Dentistry","author":"Adell R.","year":"1985"},{"key":"e_1_2_6_4_1","first-page":"233","article-title":"Reconstruction of severely resorbed edentulous maxillae using osseointegrated fixtures in inmediate autogenous bone grafts","volume":"5","author":"Adell R.","year":"1990","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9785(81)80077-4"},{"key":"e_1_2_6_6_1","first-page":"11","article-title":"The long\u2010term efficacy of currently used dental implants. A review and proposed criteria of success","volume":"1","author":"Albrektsson T.","year":"1996","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_7_1","first-page":"377","article-title":"Guided tissue regeneration for implants placed into extraction sockets and for implant dehiscences","volume":"10","author":"Becker W.","year":"1990","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_8_1","first-page":"93","article-title":"Bone formation at dehisced dental implant sites treated with implant augmentation material","volume":"10","author":"Becker W.","year":"1990","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1991.62.11.703"},{"key":"e_1_2_6_10_1","first-page":"31","article-title":"Immediate placement of titanium implants into fresh extraction sockets protected by e\u2010PTFE membrane barriers. A clinical multicenter study","volume":"9","author":"Becker W.","year":"1994","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_11_1","volume-title":"Tissue\u2010integrated Prostheses. Osseointegration in Clinical Dentistry","author":"Br\u00e5nemark P.\u2010I.","year":"1985"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1990.010104.x"},{"key":"e_1_2_6_13_1","first-page":"29","article-title":"Localized ridge augmentation using guided bone regeneration. I. Surgical procedure in the maxilla","volume":"13","author":"Buser D.","year":"1993","journal-title":"International Journal of Periodontics & Restorative Dentistry."},{"key":"e_1_2_6_14_1","first-page":"11","article-title":"Localized ridge augmentation using guided bone regeneration. II. Surgical procedure in the mandible","volume":"15","author":"Buser D.","year":"1995","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070212.x"},{"key":"e_1_2_6_16_1","first-page":"1490","article-title":"Membrane technic\/oral implantology. The simultaneous use of membranes in implants with peri\u2010implant bone defects","volume":"102","author":"Buser D.","year":"1992","journal-title":"Schweizer Monatsschrift f\u00fcr Zahnmedizin"},{"key":"e_1_2_6_17_1","first-page":"7","article-title":"Treatment of the atrophic edentulous maxilla with implant\u2010supported overdentures","volume":"11","author":"Chan M.F.W.\u2010Y.","year":"1998","journal-title":"International Journal of Prosthodontics"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1991.74.3.0487"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1991.020401.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/02844319009004514"},{"key":"e_1_2_6_21_1","first-page":"312","article-title":"Treatment of fenestration and dehiscence bone defects around oral implants using the guided tissue regeneration technique","volume":"10","author":"Dahlin C.","year":"1995","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_22_1","first-page":"273","article-title":"Membrane induced bone augmentation at titanium implants. A report on ten fixtures followed from 1 to 3 years after loading","volume":"11","author":"Dahlin C.","year":"1991","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198805000-00004"},{"key":"e_1_2_6_24_1","first-page":"19","article-title":"Generation of new bone around titanium implants using a membrane technique","volume":"4","author":"Dahlin C.","year":"1989","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_25_1","first-page":"142","article-title":"Early failures in 4641 consecutively placed Br\u00e5nemark dental implants","volume":"6","author":"Friberg B.","year":"1991","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_26_1","first-page":"17","article-title":"Success and failure rates of osseointegrated implants in function in regenerated bone for 6 to 51 months","volume":"12","author":"Fugazzotto P.A.","year":"1997","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_27_1","first-page":"468","volume-title":"Proceedings of the Third European Workshop in Periodontology. Implant Dentistry, Ittigen","author":"H\u00e4mmerle C.H.","year":"1999"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.29.s3.14.x"},{"key":"e_1_2_6_29_1","first-page":"233","article-title":"Bone regeneration around titanium dental implants in dehisced defect sites. A clinical study","volume":"7","author":"Jovanovic S.A.","year":"1992","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_30_1","first-page":"333","article-title":"Immediate implant placement into extraction sites","volume":"9","author":"Lazzara R.J.","year":"1989","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9785(86)80011-4"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1993.040302.x"},{"key":"e_1_2_6_33_1","first-page":"599","article-title":"Soft tissue and marginal bone conditions at osseointegrated implants that have exposed threads","volume":"11","author":"Lekholm U.","year":"1996","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_34_1","first-page":"199","volume-title":"Tissue\u2010integrated Prostheses: Osseointegration in Clinical Dentristy","author":"Lekholm U.","year":"1985"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.4.512"},{"key":"e_1_2_6_36_1","first-page":"169","article-title":"Guided bone regeneration of bone defects associated with implants","volume":"15","author":"Mellonig J.T.","year":"1995","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_37_1","first-page":"109","article-title":"Guided tissue regeneration and endosseous dental implants","volume":"13","author":"Mellonig J.T.","year":"1993","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_38_1","first-page":"97","article-title":"Enhancement of the damaged edentulous ridge to receive dental implants","volume":"12","author":"Nevins M.","year":"1992","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_39_1","first-page":"35","article-title":"Implants in regenerated bone","volume":"18","author":"Nevins M.","year":"1998","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1991.tb02322.x"},{"key":"e_1_2_6_41_1","first-page":"9","article-title":"Bone regeneration adjacent to titanium dental implants using guided tissue regeneration","volume":"5","author":"Nyman S.","year":"1990","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1990.61.3.157"},{"key":"e_1_2_6_43_1","first-page":"167","article-title":"A comparative study of the effectiveness of e\u2010PTFE membranes with and without early exposure during the healing period","volume":"14","author":"Simion M.","year":"1994","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_44_1","first-page":"40","article-title":"Guided tissue regeneration in osseointegrated implants. II","volume":"1","author":"Simion M.","year":"1991","journal-title":"Italian Journal of Osseointegration"},{"key":"e_1_2_6_45_1","first-page":"199","article-title":"Qualitative and quantitative comparative study on different filling materials used in bone tissue regeneration","volume":"14","author":"Simion M.","year":"1994","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_46_1","first-page":"497","article-title":"Vertical ridge augmentation using a membrane technique associated with osseointegrated implants","volume":"14","author":"Simion M.","year":"1994","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1991.tb02321.x"},{"key":"e_1_2_6_48_1","first-page":"355","article-title":"Long\u2010term results of implants treated with guided bone regeneration","volume":"16","author":"Zitzmann N.U.","year":"2001","journal-title":"International Journal of Oral & Maxillofacial Implants"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0501.2005.01106.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0501.2005.01106.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T10:37:34Z","timestamp":1697452654000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0501.2005.01106.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,9]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["10.1111\/j.1600-0501.2005.01106.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0501.2005.01106.x","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2,9]]}}}