{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T10:08:59Z","timestamp":1718964539878},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T00:00:00Z","timestamp":1152230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:p><jats:bold>Abstract: <\/jats:bold> The purpose of this study was to explore morphologic, functional, and behavioral effects of rough (sandblasted\u2010large grid\/acid\u2010etched (SLA) and TiO<jats:sub>2<\/jats:sub> blasted), mechanically polished, and mechanochemically polished titanium implant surfaces on nerves. The compound action potentials (cAPs) of sciatic nerves of sacrificed Wistar rats (<jats:italic>n<\/jats:italic>=10) were quantified at the <jats:italic>in vitro<\/jats:italic> level, while contacting disk\u2010shaped test specimens. The test specimens were also implanted directly on the sciatic nerves of another group of animals (<jats:italic>n<\/jats:italic>=33), hot\u2010plate tests were undertaken for 10 consecutive days, and then the animals were sacrificed. Quantification of signal transduction speeds and cAPs of the nerves of these animals were undertaken at the <jats:italic>in vitro<\/jats:italic> level. Finally, the nerves were processed for histologic analysis. The signal transduction speeds and duration of cAPs of all groups were similar (<jats:italic>P<\/jats:italic>&gt;0.05), whereas the amplitudes of cAPs of nerves contacting SLA implants were higher than those of TiO<jats:sub>2<\/jats:sub> blasted and mechanochemically polished surfaces (<jats:italic>P<\/jats:italic>&lt;0.05). Response latencies of nerves contacting mechanically polished specimens were slightly higher than the other groups (<jats:italic>P<\/jats:italic>&gt;0.05). Histologic evaluations did not reveal any signs of adverse tissue response adjacent to specimens tested. Rough and polished titanium implant surfaces lead to similar neural response <jats:italic>in vivo<\/jats:italic> and <jats:italic>in vitro<\/jats:italic> that fall into physiologic limits.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2006.01255.x","type":"journal-article","created":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T08:30:13Z","timestamp":1152261013000},"page":"541-547","source":"Crossref","is-referenced-by-count":2,"title":["Neural response to sandblasted\/acid\u2010etched, TiO<sub>2<\/sub>\u2010blasted, polished, and mechanochemically polished\/nanostructured titanium implant surfaces"],"prefix":"10.1111","volume":"17","author":[{"given":"Mehmet A.","family":"Onur","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aysun","family":"Sezgin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aylin","family":"G\u00fcrp\u03b9nar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei","family":"Sommer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K\u03b9van\u00e7","family":"Ak\u00e7a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"\u00c7ehreli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2000.93.4.0711"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0196-9781(88)90023-X"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1838(88)90016-1"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2003.140303.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1970.sp009299"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(03)00218-7"},{"key":"e_1_2_6_8_1","doi-asserted-by":"crossref","first-page":"I\u20101","DOI":"10.1161\/01.cir.0000032892.55215.b5","article-title":"First clinical results with a new mechanical connector for distal coronary artery anatomoses in CABG","volume":"106","author":"Eckstein F.S.","year":"2002","journal-title":"Circulation"},{"key":"e_1_2_6_9_1","first-page":"165","volume-title":"Bone","author":"Herskovits M.S.","year":"1990"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00319037"},{"key":"e_1_2_6_11_1","first-page":"75","volume-title":"Osseoperception","author":"Jacobs R.","year":"1998"},{"key":"e_1_2_6_12_1","first-page":"463","article-title":"Endosseous implant placement in conjunction with inferior alveolar nerve transposition","volume":"12","author":"Kan J.Y.","year":"1997","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_13_1","first-page":"179","volume-title":"Clinical Applications of Biomaterials. 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