{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:28:34Z","timestamp":1790144914030,"version":"4.0.1"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,12,5]],"date-time":"2006-12-05T00:00:00Z","timestamp":1165276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2007,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives: <\/jats:bold> The aim of the following investigation was to quantify the resorption rate of tissue\u2010engineered bone grafts in the maxillary sinus using volume measurements.<\/jats:p><jats:p><jats:bold>Material and methods: <\/jats:bold> Sinus floor augmentation using autologous bone grafts from the iliac crest (<jats:italic>n<\/jats:italic>=17, group 1) was compared with commercially produced transplants of human cells seeded on polyglycolid\u2013polylactid (PLGA) scaffolds (Oral Bone<jats:sup>\u00ae<\/jats:sup>) (<jats:italic>n<\/jats:italic>=14, group 2).<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> The total resorption rate for autologous transplants 3 months post operation was 29%, while the tissue\u2010engineered bone showed a resorption rate of 90%.<\/jats:p><jats:p>The autologous bone had a bone density of up to 266\u2013551 Hounsfield units (HU), while sufficient mineralization of tissue\u2010engineered bone was found in only one case (152\u2003HU).<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> In this clinical study, the use of autologous cancellous bone grafts in sinus augmentation was more reliable than scaffolds containing cultured osteoblasts. Further tissue\u2010engineered bone transplants should be examined to draw general conclusions about the use of tissue\u2010engineered grafts compared with autologous bone grafts for maxillary sinus augmentation.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2006.01295.x","type":"journal-article","created":{"date-parts":[[2006,12,5]],"date-time":"2006-12-05T18:33:51Z","timestamp":1165343631000},"page":"69-73","source":"Crossref","is-referenced-by-count":77,"title":["Bone formation after sinus augmentation with engineered bone"],"prefix":"10.1111","volume":"18","author":[{"given":"Christoph","family":"Zizelmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Schoen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc Christian","family":"Metzger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer","family":"Schmelzeisen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Schramm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Britta","family":"Dott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai\u2010Hendrik","family":"Bormann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils Claudius","family":"Gellrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,12,5]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"613","article-title":"Grafting of the maxillary sinus floor with autogenous marrow and bone","volume":"38","author":"Boyne P.J.","year":"1980","journal-title":"Journal of Oral Surgery"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2003.08.003"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2004.04.051"},{"key":"e_1_2_6_5_1","first-page":"11","article-title":"Report of the sinus consensus conference of 1996","volume":"13","author":"Jensen O.T.","year":"1998","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.dmfr.4600601"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8240.2003.tb00298.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199903010-00003"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10006-002-0404-5"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200111000-00019"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0901-5027(06)80029-9"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008994715605"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-5182(02)00163-4"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-2607(01)00116-X"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","unstructured":"Tatum H.(1977) Lectures presented at the Alabama Implant Study Group. 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