{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T23:45:51Z","timestamp":1793317551734,"version":"4.5.0"},"reference-count":50,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,12,20]],"date-time":"2006-12-20T00:00:00Z","timestamp":1166572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives: <\/jats:bold> The aim of the present study was to evaluate and compare naturally occuring and ligature\u2010induced peri\u2010implantitis bone defects in humans and dogs.<\/jats:p><jats:p><jats:bold>Material and Methods: <\/jats:bold> Twenty\u2010four partially and fully edentulous patients undergoing peri\u2010implant bone augmentation procedures due to advanced peri\u2010implant infections were included in this study (<jats:italic>n<\/jats:italic>=40 implants). Furthermore, peri\u2010implantitis was induced by ligature placement and plaque accumulation in five beagle dogs for three months following implant insertion (<jats:italic>n<\/jats:italic>=15 implants). The ligatures were removed when about 30% of the initial bone was lost. During open flap surgery, configuration and defect characteristics of the peri\u2010implant bone loss were recorded in both humans and dogs.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Open flap surgery generally revealed two different classes of peri\u2010implant bone defects. While Class I defects featured well\u2010defined intrabony components, Class II defects were characterized by consistent horizontal bone loss. The allocation of intrabony components of Class I defects regarding the implant body allowed a subdivision of five different configurations (Classes Ia\u2013e). In particular, human defects were most frequently Class Ie (55.3%), followed by Ib (15.8%), Ic (13.3%), Id (10.2%), and Ia (5.4%). Similarly, bone defects in dogs were also most frequently Class Ie (86.6%), while merely two out of 15 defects were Classes Ia and Ic (6.7%, respectively).<\/jats:p><jats:p><jats:bold>Conclusions: <\/jats:bold> Within the limits of the present study, it might be concluded that configurations and sizes of ligature\u2010induced peri\u2010implantitis bone defects in dogs seemed to resemble naturally occurring lesions in humans.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2006.01320.x","type":"journal-article","created":{"date-parts":[[2006,12,21]],"date-time":"2006-12-21T08:21:47Z","timestamp":1166689307000},"page":"161-170","source":"Crossref","is-referenced-by-count":189,"title":["Comparison of naturally occurring and ligature\u2010induced peri\u2010implantitis bone defects in humans and dogs"],"prefix":"10.1111","volume":"18","author":[{"given":"Frank","family":"Schwarz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Herten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Sager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Bieling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Sculean","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,12,20]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"365","volume-title":"Proceedings of the 1st European Workshop on Periodontology","author":"Albrektsson T.","year":"1994"},{"key":"e_1_2_6_3_1","first-page":"11","article-title":"Microbial aspects of failing osseointegrated dental implants in humans","volume":"10","author":"Alcoforado G.A.","year":"1991","journal-title":"Journal de Parodontologie"},{"key":"e_1_2_6_4_1","first-page":"9","article-title":"Implant surface preparation","volume":"3","author":"Baier R.E.","year":"1988","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_6_5_1","first-page":"533","article-title":"Experimentally induced peri\u2010implantitis","volume":"15","author":"Baron M.","year":"2000","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_6_6_1","first-page":"31","article-title":"Clinical and microbiologic findings that may contribute to dental implant failure","volume":"5","author":"Becker W.","year":"1990","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_6_7_1","first-page":"125","article-title":"Treatment of peri\u2010implantitis defects with autogenous bone grafts","volume":"15","author":"Behneke A.","year":"2000","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_6_8_1","first-page":"659","article-title":"Peri\u2010implant care of ailing implants with the carbon dioxide laser","volume":"16","author":"Deppe H.","year":"2001","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070404.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0909-8836..t01-6-.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1988.tb01016.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1958.29.4.272"},{"key":"e_1_2_6_13_1","first-page":"282","article-title":"Treatment of ligature\u2010induced peri\u2010implantitis using guided tissue regeneration","volume":"8","author":"Grunder U.","year":"1993","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_6_14_1","first-page":"374","article-title":"Lethal photosensitization, autogenous bone, and e\u2010PTFE membrane for the treatment of peri\u2010implantitis","volume":"15","author":"Haas R.","year":"2000","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2002.130402.x"},{"key":"e_1_2_6_16_1","first-page":"168","article-title":"Treatment of peri\u2010implantitis using guided bone regeneration and bone grafts, alone or in combination, in beagle dogs. 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