{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:47:37Z","timestamp":1791161257637,"version":"4.1.0"},"reference-count":48,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T00:00:00Z","timestamp":1157068800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives: <\/jats:bold> The objective of this systematic review was to critically evaluate marginal soft\u2010tissue aspects at implants subjected to immediate loading or immediate restoration.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> An electronic Medline search from 1966 up to August 2005 was conducted to identify prospective and retrospective studies on immediate implant loading. The search strategy was complemented by hand searching in peer\u2010reviewed journals. Studies reporting on soft\u2010tissue aspects at implants subjected to immediate loading or immediate restoration and with a follow\u2010up time of at least 1 year were included. Assessment of identified studies and data extraction was performed independently by two reviewers. An attempt was made to isolate and categorize studies with similar protocols in order to identify trends and relevant factors. Variables that were considered included marginal and interproximal soft\u2010tissue stability, marginal plaque accumulation, probing depth, bleeding on probing, peri\u2010implant mucositis and peri\u2010implantitis.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> From an initial yield of 581 titles, 240 articles were selected for text analysis, finally resulting in 17 studies that met the inclusion criteria. Six studies on immediate implant loading or restoration were controlled studies, whereas the remainder was prospective case series. Seven studies reported on a 1\u2010year data, and the longest follow\u2010up within the included studies was 4 years. The total number of patients treated within the 17 studies was 432 including a total 706 implants studied. Overall, the articles reported on many different procedures and follow\u2010up times, time points and evaluated soft\u2010tissue parameters varied considerably between the different articles.<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> Within the limits of the evaluated data it can be cautiously concluded that once immediately loaded or restored implants integrate successfully, they appear to show a soft\u2010tissue reaction with regard to periodontal as well as morphologic aspects comparable with those of conventionally loaded implants. However, follow\u2010up periods are generally short, number of patients and\/or implants per study are few, and most studies present only limited data on peri\u2010implant soft\u2010tissue evaluation. More accurate long\u2010term studies with a stronger study design (i.e., RCT) reporting more detailed on treatment and follow\u2010up protocols are required to allow for proper comparisons and conclusions.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2006.01355.x","type":"journal-article","created":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T19:31:27Z","timestamp":1157139087000},"page":"82-92","source":"Crossref","is-referenced-by-count":48,"title":["A systematic review of marginal soft tissue at implants subjected to immediate loading or immediate restoration"],"prefix":"10.1111","volume":"17","author":[{"given":"Roland","family":"Glauser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Zembic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph H.F.","family":"H\u00e4mmerle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,9]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"61","article-title":"Immediate loading of single\u2010tooth implants in the posterior region","volume":"20","author":"Abboud M.","year":"2005","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_7_3_1","first-page":"11","article-title":"The long\u2010term efficacy of currently used dental implants","volume":"1","author":"Albrektsson T.","year":"1986","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2003.tb00183.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2005.04.015"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070401.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.1997.tb00312.x"},{"key":"e_1_2_7_8_1","first-page":"512","article-title":"Restoration of partially edentulous patients using dental implants with a microtextured surface","volume":"18","author":"Cannizzaro G.","year":"2003","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_7_9_1","first-page":"76","article-title":"Early and immediate restoration and loading of implants in completely edentulous patients","volume":"19","author":"Chiapasco M.","year":"2004","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_7_10_1","first-page":"537","article-title":"Implant\u2010retained mandibular overdentures with Br\u00e5nemark System Mk II implants","volume":"16","author":"Chiapasco M.","year":"2001","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.1997.tb00007.x"},{"key":"e_1_2_7_12_1","first-page":"109","article-title":"Consensus statements and recommended clinical procedures regarding loading protocols for endosseous dental implants","volume":"19","author":"Cochran D.L.","year":"2004","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_7_13_1","first-page":"855","article-title":"Immediate restoration of single\u2010tooth implants in mandibular molar sites","volume":"19","author":"Cornelini R.","year":"2004","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_7_14_1","first-page":"439","article-title":"Immediate restoration of implants placed into fresh extraction sockets for single\u2010tooth replacement","volume":"25","author":"Cornelini R.","year":"2005","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2003.tb00176.x"},{"key":"e_1_2_7_16_1","first-page":"12","article-title":"Immediate functional loading of Br\u00e5nemark single tooth implants. 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