{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T16:42:17Z","timestamp":1773247337782,"version":"3.50.1"},"reference-count":57,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,4,18]],"date-time":"2007-04-18T00:00:00Z","timestamp":1176854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2007,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim: <\/jats:bold> To evaluate histologically the morphology and characteristics of bone chips harvested intraorally by Safescraper<jats:sup>\u00ae<\/jats:sup>, a specially designed cortical bone collector.<\/jats:p><jats:p><jats:bold>Material and methods: <\/jats:bold> Bone chips harvested near a bone defect or in other intraoral sites were grafted into a post\u2010extractive socket or applied in procedures for maxillary sinus floor augmentation or guided bone regeneration. Core biopsies were performed at implant insertion. Undecalcified specimens embedded in PMMA were studied by histology, histochemistry and SEM.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Intraoral harvesting by Safescraper<jats:sup>\u00ae<\/jats:sup> provided a simple, clinically effective regenerative procedure with low morbidity for collecting cortical bone chips (0.9\u20131.7\u2003mm in length, roughly 100\u2003\u03bcm thick). Chips had an oblong or quadrangular shape and contained live osteocytes (mean viability: 45\u201372%). Bone chip grafting produced newly formed bone tissue suitable for implant insertion. Trabecular bone volume measured on biopsies decreased with time (from 45\u201355% to 23%). Grafted chips made up 50% or less of the calcified tissue in biopsies. Biopsies presented remodeling activities, new bone formation by apposition and live osteocytes (35% or higher).<\/jats:p><jats:p><jats:bold>Discussion and conclusions: <\/jats:bold> In conclusion, Safescraper<jats:sup>\u00ae<\/jats:sup> is capable of collecting adequate amounts of cortical bone chips from different intraoral sites. The procedure is effective for treating alveolar defects for endosseous implant insertion and provides good healing of small bone defects after grafting with bone chips. The study indicates that Safescraper<jats:sup>\u00ae<\/jats:sup> is a very useful device for in\u2010office bone harvesting procedures in routine peri\u2010implant bone regeneration.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2007.01368.x","type":"journal-article","created":{"date-parts":[[2007,5,3]],"date-time":"2007-05-03T17:47:23Z","timestamp":1178214443000},"page":"525-533","source":"Crossref","is-referenced-by-count":36,"title":["A novel bone scraper for intraoral harvesting: a device for filling small bone defects"],"prefix":"10.1111","volume":"18","author":[{"given":"Davide","family":"Zaffe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdinando","family":"D'Avenia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,4,18]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2003.12.036"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00656.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-005-3575-4"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-5182(05)80411-1"},{"key":"e_1_2_5_6_1","first-page":"613","article-title":"Grafting of the maxillary sinus floor with autogenous marrow and bone","volume":"38","author":"Boyne P.J.","year":"1980","journal-title":"Journal of Oral Surgery"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-002-2109-z"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1990.010104.x"},{"key":"e_1_2_5_9_1","first-page":"29","article-title":"Localized ridge augmentation using guided bone regeneration. 1. 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