{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T09:16:53Z","timestamp":1793870213927,"version":"4.6.1"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,4,19]],"date-time":"2007-04-19T00:00:00Z","timestamp":1176940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2007,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives: <\/jats:bold> The aim of this experimental study was to evaluate if low\u2010level laser treatment (LLLT) enhances bone regeneration and osseointegration of dental implants in a sinus graft model.<\/jats:p><jats:p><jats:bold>Material and methods: <\/jats:bold> Twelve sheep underwent a bilateral sinus floor elevation procedure with cancellous bone from the iliac crest. Implant insertion followed 4 weeks (six sheep) and 12 weeks (six sheep) later. Sixteen weeks after second\u2010stage surgery, animals were sacrificed. Unilaterally, the grafted sinus and during the second\u2010stage surgery the implant sites were irradiated intraoperatively and three times during the first postoperative week with a diode laser (75\u2003mW, 680\u2003nm). The overall energy density per irradiation was 3\u20134\u2003J\/cm<jats:sup>2<\/jats:sup>. Biopsies of the augmented area were obtained during implant insertion and after scarification.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Bone regeneration within the grafted sinus histomorphometric analysis hardly differed between control and test side both 4 and 12 weeks after sinus grafting. Osseointegration measurements resulted in a significantly higher bone\/implant contact (BIC) on the test side (<jats:italic>P<\/jats:italic>=0.045). Further evaluation of peri\u2010implant bone tends to amount in significant higher percentage on the laser side (<jats:italic>P<\/jats:italic>=0.053).<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> The presented experimental study on sheep did not confirm a positive LLLT effect on bone regeneration within a cancellous sinus graft. Nevertheless, LLLT possibly has a positive effect on osseointegration of dental implants inserted after sinus augmentation.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2007.01369.x","type":"journal-article","created":{"date-parts":[[2007,5,3]],"date-time":"2007-05-03T17:07:21Z","timestamp":1178212041000},"page":"517-524","source":"Crossref","is-referenced-by-count":63,"title":["Influence of low\u2010level laser treatment on bone regeneration and osseointegration of dental implants following sinus augmentation: An experimental study on sheep"],"prefix":"10.1111","volume":"18","author":[{"given":"Norbert","family":"Jakse","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Payer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Tangl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Berghold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Kirmeier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Lorenzoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(94)00006-9"},{"key":"e_1_2_7_3_1","first-page":"197","article-title":"Die Trenn\u2010D\u00fcnnschliff\u2010technik zur Herstellung histologischer Pr\u00e4parate von nicht schneidbaren Geweben und Materialien","volume":"34","author":"Donath K.","year":"1988","journal-title":"Der Pr\u00e4parator"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2000.011006540.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2002.130308.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2003.00872.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1081\/BIO-100103047"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1998.090206.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2003.00928.x"},{"key":"e_1_2_7_10_1","first-page":"1","article-title":"The effect of low level laser irradiation on implant\u2010tissue interaction. 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