{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T11:06:40Z","timestamp":1793963200307,"version":"4.8.0"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2007,6,30]],"date-time":"2007-06-30T00:00:00Z","timestamp":1183161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2007,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives: <\/jats:bold> To evaluate healing of marginal defects in immediate transmucosal implants grafted with anorganic bovine bone, and to assess mucosal and radiographic outcomes 3\u20134 years following restoration.<\/jats:p><jats:p><jats:bold>Material and methods: <\/jats:bold> Thirty immediate transmucosal implants in maxillary anterior extraction sites of 30 patients randomly received BioOss<jats:sup>\u2122<\/jats:sup> (<jats:italic>N<\/jats:italic>=10; BG), BioOss<jats:sup>\u2122<\/jats:sup> and resorbable collagen membrane (<jats:italic>N<\/jats:italic>=10; BG+M) or no graft (<jats:italic>N<\/jats:italic>=10; control).<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Vertical defect height (VDH) reductions of 81.2\u00b15%, 70.5\u00b117.4% and 68.2\u00b116.6%, and horizontal defect depth (HDD) reductions of 71.7\u00b134.3%, 81.7\u00b133.7% and 55\u00b128.4% were observed for BG, BG+M and control groups, respectively, with no significant inter\u2010group differences. Horizontal resorption was significantly greater in control group (48.3\u00b19.5%) when compared with BG (15.8\u00b116.9%) and BG+M (20\u00b121.9%) groups (<jats:italic>P<\/jats:italic>=0.000). Ten sites (33.3%) exhibited recession of the mucosa after 6 months; eight (26.7%) had an unsatisfactory esthetic result post\u2010restoration due to recession. Mucosal recession was significantly associated (<jats:italic>P<\/jats:italic>=0.032) with buccally positioned implants (HDD 1.1\u00b10.3\u2003mm) when compared with lingually positioned implants (HDD 2.3\u00b10.6\u2003mm). In 19 patients followed for a mean of 4.0\u00b10.7 years, marginal mucosa and bone levels remained stable following restoration.<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> BioOss<jats:sup>\u2122<\/jats:sup> significantly reduced horizontal resorption of buccal bone. There is a risk of mucosal recession and adverse soft tissue esthetics with immediate implant placement. However, this risk may be reduced by avoiding a buccal position of the implant in the extraction socket.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2007.01388.x","type":"journal-article","created":{"date-parts":[[2007,6,30]],"date-time":"2007-06-30T13:48:15Z","timestamp":1183211295000},"page":"552-562","source":"Crossref","is-referenced-by-count":305,"title":["A prospective clinical study of non\u2010submerged immediate implants: clinical outcomes and esthetic results"],"prefix":"10.1111","volume":"18","author":[{"given":"Stephen T.","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan B.","family":"Darby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric 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