{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T15:36:37Z","timestamp":1784648197886,"version":"3.55.0"},"reference-count":57,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,2,11]],"date-time":"2008-02-11T00:00:00Z","timestamp":1202688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives: <\/jats:bold> To investigate the association between keratinized mucosa (KM) width and mucosal thickness (MTh) with clinical and immunological parameters around dental implants.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> Sixty\u2010three functioning dental implants (3I osseotite) were examined. Clinical examinations included plaque index (PI), probing depth (PD), bleeding on probing (BOP), KM width, MTh and buccal mucosal recession (MR). Peri\u2010implant crevicular fluid (PICF) samples were collected for PgE2 assay.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> KM width ranged from 0 to 7\u2003mm (mean 2.5\u00b12), MTh ranged from 0.38 to 2.46\u2003mm (mean 1.11\u00b10.4) and the mean MR was 0.62\u2003mm, ranging from 0 to 3\u2003mm.<\/jats:p><jats:p>A negative correlation was found between MTh and MR (<jats:italic>r<\/jats:italic>=\u22120.32, <jats:italic>P<\/jats:italic>=0.01); Likewise, KM width showed a negative correlation with MR, periodontal attachment level (PAL) and PgE2 levels (<jats:italic>r<\/jats:italic>=\u22120.41, <jats:italic>P<\/jats:italic>&lt;0.001; <jats:italic>r<\/jats:italic>=\u22120.26, <jats:italic>P<\/jats:italic>=0.04; <jats:italic>r<\/jats:italic>=\u22120.26, <jats:italic>P<\/jats:italic>=0.04, respectively). In contrast, a positive correlation was found between KM width and PD (<jats:italic>r<\/jats:italic>=0.27, <jats:italic>P<\/jats:italic>=0.03).<\/jats:p><jats:p>When data were dichotomized by KM width, a wider mucosal band (&gt;1\u2003mm) was associated with less MR compared with narrow (\u22641\u2003mm) band (0.27 and 0.9\u2003mm, respectively, <jats:italic>P<\/jats:italic>=0.001). A wider KM band was also associated with a greater PD (3.13\u2003mm) compared with a narrow band (2.66\u2003mm, <jats:italic>P<\/jats:italic>=0.04).<\/jats:p><jats:p>Similarly, a thick mucosa (\u22651\u2003mm) was associated with lesser recession compared with a thin (&lt;1\u2003mm) mucosa (0.45 and 0.9\u2003mm, respectively, <jats:italic>P<\/jats:italic>=0.04).<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> The KM around dental implants affects both the clinical and the immunological parameters at these sites. These findings are of special importance in the esthetic zone, where thin and narrow KM may lead to a greater MR.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2007.01492.x","type":"journal-article","created":{"date-parts":[[2008,2,11]],"date-time":"2008-02-11T11:01:50Z","timestamp":1202727710000},"page":"387-392","source":"Crossref","is-referenced-by-count":196,"title":["The dimensions of keratinized mucosa around implants affect clinical and immunological parameters"],"prefix":"10.1111","volume":"19","author":[{"given":"Hadar","family":"Zigdon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli E.","family":"Machtei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,2,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1957.28.2.106"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01178.x"},{"key":"e_1_2_7_4_1","first-page":"71","article-title":"Surgical thickening of the existing gingiva and reconstruction of interdental papillae around implant\u2010supported restorations","volume":"22","author":"Azzi R.","year":"2002","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1991.020206.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(90)90531-6"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1962.33.2.120"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1962.33.4.354"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1963.34.3.201"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1970.41.10.581"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1997.080508.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(91)90155-6"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.050393"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb00861.x"},{"key":"e_1_2_7_15_1","first-page":"6570","article-title":"The double papillae repositioned flap in periodontal therapy","volume":"39","author":"Cohen D.W.","year":"1968","journal-title":"Journal of Periodontology"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1962.33.2.140"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1982.53.6.349"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1962.33.4.328"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(54)90216-9"},{"key":"e_1_2_7_20_1","unstructured":"Greves A.(1977)Width of attached gingival and vestibular depth in relation to gingival health. Thesis. University of Amsterdam."},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1956.27.2.92"},{"key":"e_1_2_7_22_1","first-page":"404","article-title":"Strip gingival autograft used to correct mucogingival problems around implants","volume":"15","author":"Han T.J.","year":"1995","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.1.59"},{"key":"e_1_2_7_24_1","first-page":"56","article-title":"The rationale for soft\u2010tissue grafting and vestibuloplasty in association with endosseous implants","volume":"78","author":"Hoelscher D.C.","year":"1996","journal-title":"Journal of Michigan Dental Association"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1985.tb00938.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1972.43.10.623"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1992.030303.x"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1998.tb00122.x"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1992.030102.x"},{"key":"e_1_2_7_30_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1034\/j.1600-0501.1991.020101.x","article-title":"Periodontal tissue and their counterparts around endosseous implants","volume":"2","author":"Listgarten M.A.","year":"1991","journal-title":"Clinical Oral Implants Research"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1967.38.6.610"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2006.01282.x"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1563\/1548-1336(2003)029<0120:MOTPIT>2.3.CO;2"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1977.tb02273.x"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2000.027009621.x"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1954.25.1.38"},{"key":"e_1_2_7_37_1","first-page":"243","article-title":"Free gingival grafts","volume":"4","author":"Nabers J.M.","year":"1966","journal-title":"Periodontics"},{"key":"e_1_2_7_38_1","first-page":"385","article-title":"Split palatal flap. II. A surical approach for maxillary implant uncovering in cases with reduced keratinized tissue","volume":"19","author":"Nemcovsky C.E.","year":"1999","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_7_39_1","first-page":"607","article-title":"Rotated palatal flap. A surgical approach to increase keratinized tissue width in maxillary implant uncovering","volume":"22","author":"Nemcovsky C.E.","year":"2002","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1960.31.3.175"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.72.9.1236"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1177\/08959374930070020801"},{"key":"e_1_2_7_43_1","volume-title":"Oral Histology and Embryology","author":"Orban B.","year":"1944"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(48)90014-0"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.00908.x"},{"key":"e_1_2_7_46_1","first-page":"32","article-title":"The clinical, microbial, and host response characteristics of the failing implant","volume":"12","author":"Salcetti J.M.","year":"1997","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_7_47_1","first-page":"477","volume-title":"Textbook of Clinical Periodontology","author":"Seibert J.","year":"1989"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008505-199412000-00003"},{"key":"e_1_2_7_49_1","first-page":"135","article-title":"The use of the subepithelial connective tissue graft to enhance both the aesthetics and periodontal contours surrounding dental implants","volume":"20","author":"Silverstein L.H.","year":"1994","journal-title":"Journal of Oral Implantology"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008505-199412000-00004"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008505-199304000-00006"},{"key":"e_1_2_7_52_1","first-page":"317","article-title":"The role of attached gingiva in the health of peri\u2010implant tissue in dogs. 1. Clinical findings","volume":"11","author":"Strub J.R.","year":"1991","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1995.060301.x"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1983.tb01277.x"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1987.tb00964.x"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1963.34.6.487"},{"key":"e_1_2_7_57_1","first-page":"383","article-title":"Widening the zone of peri\u2010implant attached gingiva","volume":"2","author":"Yilmaz S.","year":"1994","journal-title":"Journal of Marmara University Dental Faculty"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028006517.x"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0501.2007.01492.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0501.2007.01492.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T08:08:50Z","timestamp":1697443730000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0501.2007.01492.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2,20]]},"references-count":57,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["10.1111\/j.1600-0501.2007.01492.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0501.2007.01492.x","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,2,20]]}}}