{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:24:28Z","timestamp":1777541068386,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,4,14]],"date-time":"2008-04-14T00:00:00Z","timestamp":1208131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim: <\/jats:bold> To assess the clinical and radiographic outcomes of immediate transmucosal placement of implants into molar extraction sockets.<\/jats:p><jats:p><jats:bold>Study design: <\/jats:bold> Twelve\u2010month multicenter prospective cohort study.<\/jats:p><jats:p><jats:bold>Material and methods: <\/jats:bold> Following molar extraction, tapered implants with an endosseous diameter of 4.8\u2003mm and a shoulder diameter of 6.5\u2003mm were immediately placed into the sockets. Molars with evidence of acute periapical pathology were excluded. After implant placement and achievement of primary stability, flaps were repositioned and sutured allowing a non\u2010submerged, transmucosal healing. Peri\u2010implant marginal defects were treated according to the principles of guided bone regeneration (GBR) by means of deproteinized bovine bone mineral particles in conjunction with a bioresrobable collagen membrane. Standardized radiographs were obtained at baseline and 12 months thereafter. Changes in depth and width of the distance from the implant shoulder (IS) and from the alveolar crest (AC) to the bottom of the defect (BD) were assessed.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Eighty\u2010two patients (42 males and 40 females) were enrolled and followed for 12 months. They contributed with 82 tapered implants. Extraction sites displayed sufficient residual bone volume to allow primary stability of all implants. Sixty\u2010four percent of the implants were placed in the areas of 36 and 46. GBR was used in conjunction with the placement of all implants. No post\u2010surgical complications were observed. All implants healed uneventfully yielding a survival rate of 100% and healthy soft tissue conditions after 12 months. Radiographically, statistically significant changes (<jats:italic>P<\/jats:italic>&lt;0.0001) in mesial and distal crestal bone levels were observed from baseline to the 12\u2010month follow\u2010up.<\/jats:p><jats:p><jats:bold>Conclusions: <\/jats:bold> The findings of this 12\u2010month prospective cohort study showed that immediate transmucosal implant placement represented a predictable treatment option for the replacement of mandibular and maxillary molars lost due to reasons other than periodontitis including vertical root fractures, endodontic failures and caries.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2008.01541.x","type":"journal-article","created":{"date-parts":[[2008,4,14]],"date-time":"2008-04-14T22:48:02Z","timestamp":1208213282000},"page":"476-482","source":"Crossref","is-referenced-by-count":35,"title":["Immediate transmucosal implant placement in molar extraction sites: a 12\u2010month prospective multicenter cohort study"],"prefix":"10.1111","volume":"19","author":[{"given":"C.","family":"Cafiero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Annibali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Gherlone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. R.","family":"Grassi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Gualini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Magliano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Romeo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Tonelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. P.","family":"Lang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. E.","family":"Salvi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the ITI Study Group Italia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,4,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00642.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00726.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2006.01315.x"},{"key":"e_1_2_6_5_1","first-page":"242","article-title":"Wide\u2010diameter implant placement and internal sinus membrane elevation in the immediate postextraction phase","volume":"18","author":"Artzi Z.","year":"2003","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_6_1","first-page":"376","article-title":"Guided tissue regeneration for implants placed into extraction sockets and for implant dehiscences","volume":"10","author":"Becker W.","year":"1990","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2003.140105.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00565.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00502.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2006.01270.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070309.x"},{"key":"e_1_2_6_12_1","first-page":"12","article-title":"Immediate or early placement of implants following tooth extraction","volume":"19","author":"Chen S.T.","year":"2004","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_13_1","first-page":"522","article-title":"Successful bone formation at immediate transmucosal implants","volume":"13","author":"H\u00e4mmerle C.H.F.","year":"1998","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_14_1","first-page":"26","article-title":"Consensus statements and recommended clinical procedures regarding the placement of implants in extraction sockets","volume":"19","author":"H\u00e4mmerle C.H.F.","year":"2004","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00606.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.1969.tb06001.x"},{"key":"e_1_2_6_17_1","first-page":"19","article-title":"The immediate implant","volume":"6","author":"Krump J.L.","year":"1991","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1994.050306.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2006.01371.x"},{"key":"e_1_2_6_20_1","first-page":"332","article-title":"Immediate implant placement into extraction sites","volume":"9","author":"Lazzara R.J.","year":"1989","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_6_21_1","first-page":"9","article-title":"Bone regeneration adjacent to titanium dental implants using guided tissue regeneration","volume":"5","author":"Nyman S.","year":"1990","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(67)90046-7"},{"key":"e_1_2_6_23_1","first-page":"313","article-title":"Bone healing and soft tissue contour changes following single\u2010tooth extraction","volume":"23","author":"Schropp L.","year":"2003","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_6_24_1","first-page":"348","article-title":"The T\u00fcbingen immediate implant in clinical studies","volume":"33","author":"Schulte W.","year":"1978","journal-title":"Deutsche Zahn\u00e4rztliche Zeitschrift"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.5.839"},{"key":"e_1_2_6_26_1","first-page":"55","article-title":"The immediate placement of dental implants into fresh maxillary extraction sites","volume":"3","author":"Sevor J.","year":"1991","journal-title":"Practical Periodontics and Aesthetic Dentistry"},{"key":"e_1_2_6_27_1","first-page":"206","article-title":"The immediate implant","volume":"12","author":"Werbitt M.J.","year":"1992","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_6_28_1","first-page":"185","article-title":"Guided tissue regeneration around dental implants in immmediate and recent extraction sites","volume":"12","author":"Wilson T.G.","year":"1992","journal-title":"International Journal of Periodontics and Restorative Dentistry"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0501.2008.01541.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0501.2008.01541.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T23:52:46Z","timestamp":1696981966000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0501.2008.01541.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4,14]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1111\/j.1600-0501.2008.01541.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0501.2008.01541.x","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4,14]]}}}