{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T11:00:17Z","timestamp":1789556417299,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2009,8,30]],"date-time":"2009-08-30T00:00:00Z","timestamp":1251590400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives: <\/jats:bold> Mini\u2010implants are used for orthodontic bone anchorage. The reasons for a potential instability or loss of the mini\u2010implants during treatment are multiple. Among other factors, colonization of implants with pathogenic bacteria is discussed. Therefore, the microflora associated with successful and failed mini\u2010implants has been screened.<\/jats:p><jats:p><jats:bold>Material and methods: <\/jats:bold> A total of 76 mini\u2010implants collected from 25 patients were observed during regular orthodontic treatment. Bacterial samples of eight failed and \u2013 exemplarily \u2013 four successful (control) cases were subjected to a universal <jats:italic>Bacteria<\/jats:italic>\u2010directed real\u2010time quantitative polymerase chain reaction for quantification in combination with a microarray\u2010based identification of 20 selected species.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> The failure rate in the present investigation was 10.5%. The bacterial analysis did not reveal any major difference in the total amount or species composition between control and failed mini\u2010implants. However, <jats:italic>Actinomyces viscosus<\/jats:italic> was found in four (100%) and <jats:italic>Campylobacter gracilis<\/jats:italic> in three (75%) stable controls, whereas both species were rarely found (12.5%) in failed implants.<\/jats:p><jats:p><jats:bold>Conclusions: <\/jats:bold> In the present study, the peri\u2010implant sulcus surrounding failed orthodontic mini\u2010implants did not show a specific aggressive bacterial flora.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2009.01756.x","type":"journal-article","created":{"date-parts":[[2009,8,31]],"date-time":"2009-08-31T02:03:55Z","timestamp":1251684235000},"page":"1186-1190","source":"Crossref","is-referenced-by-count":39,"title":["Microflora associated with successful and failed orthodontic 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