{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T02:04:40Z","timestamp":1791425080799,"version":"4.3.3"},"reference-count":30,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2009,8,30]],"date-time":"2009-08-30T00:00:00Z","timestamp":1251590400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background: <\/jats:bold> The question of the importance of keratinized mucosa around dental implants for the prevention of peri\u2010implant disease could not be answered in the relevant literature so far.<\/jats:p><jats:p><jats:bold>Objective: <\/jats:bold> To investigate the influence of peri\u2010implant keratinized mucosa on long\u2010term peri\u2010implant soft\u2010tissue health and stability over a period of 5 years.<\/jats:p><jats:p><jats:bold>Material and methods: <\/jats:bold> A total of 386 mandibular dental implants were placed in 73 completely edentulous patients, and subsequently restored with fixed full\u2010arch prostheses. At prosthesis delivery (baseline) and after 3, 6, 12, 18, 24, 36, 48 and 60 months, modified plaque index (mPlI), modified sulcus bleeding index (mBI), distance between implant shoulder and mucosal margin (DIM) and width of peri\u2010implant keratinized mucosa (KM) were recorded. Statistical analysis included multivariate logistic regression, multivariate ordinal logistic regression, generalized estimating equations and Bonferroni's correction.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Fifty\u2010eight patients with 307 implants completed the 5\u2010year study. Statistically significantly higher plaque accumulation on lingual sites (mean mPlI 0.67, SD 0.85), bleeding tendencies on lingual sites (mean mBI 0.22, SD 0.53) and larger soft\u2010tissue recession on buccal sites (mean DIM \u22120.69\u2003mm, SD 1.11\u2003mm) were found when the width of KM was &lt;2\u2003mm, compared to sites with\u22652\u2003mm of KM (mean mPlI 0.40, SD 0.68, <jats:italic>P<\/jats:italic>=0.001; mean mBI 0.13, SD 0.41, <jats:italic>P<\/jats:italic>&lt;0.01; mean DIM \u22120.08\u2003mm, SD 0.86\u2003mm, <jats:italic>P<\/jats:italic>&lt;0.001). The width of keratinized mucosa had no effect on bleeding tendency or plaque accumulation on buccal sites (<jats:italic>P<\/jats:italic>&gt;0.05).<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> In patients exercising good oral hygiene and receiving regular implant maintenance therapy, implants with a reduced width of &lt;2\u2003mm of peri\u2010implant keratinized mucosa were more prone to lingual plaque accumulation and bleeding as well as buccal soft\u2010tissue recession over a period of 5 years.<\/jats:p>","DOI":"10.1111\/j.1600-0501.2009.01795.x","type":"journal-article","created":{"date-parts":[[2009,8,31]],"date-time":"2009-08-31T02:04:00Z","timestamp":1251684240000},"page":"1170-1177","source":"Crossref","is-referenced-by-count":232,"title":["Five\u2010year evaluation of the influence of keratinized mucosa on peri\u2010implant soft\u2010tissue health and stability around implants supporting full\u2010arch mandibular fixed prostheses"],"prefix":"10.1111","volume":"20","author":[{"given":"Alexander Ren\u00e9","family":"Schrott","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monik","family":"Jimenez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae\u2010Woong","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Fiorellini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans\u2010Peter","family":"Weber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,9,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9785(86)80010-2"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1966.37.1.5"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1991.020206.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070401.x"},{"key":"e_1_2_7_6_1","volume-title":"Tissue\u2010Integrated Prosthesis","author":"Branemark P.I.","year":"1987"},{"key":"e_1_2_7_7_1","first-page":"766","article-title":"Vestibuloplasty with free mucosal grafts in implants in the edentulous mandible. 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