{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:22:34Z","timestamp":1761675754804},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2010,5,9]],"date-time":"2010-05-09T00:00:00Z","timestamp":1273363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives: <\/jats:bold> To compare resorption of a synthetic biphasic calcium phosphate (BCP) bone\u2013graft substitute with deproteinized bovine bone (DBB) used for human maxillary sinus augmentation.<\/jats:p><jats:p><jats:bold>Materials and methods: <\/jats:bold> Eleven patients underwent bilateral maxillary sinus floor augmentation with DBB in one side and a BCP (40%\u03b2\u2010tricalcium phosphate (\u03b2\u2010TCP) and 60% hydroxyapatite) in the contralateral side. Simultaneously, with the augmentation on each side a microimplant was placed vertically from the top of the alveolar crest penetrating the residual bone and the grafting material. Eight months after initial surgery the microimplants were retrieved with a surrounding bone core. The composition of residual graft material and surrounding bone was analysed by scanning electron microscopy and energy dispersive X\u2010ray spectroscopy.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Residual graft material of both types was present as 10\u2013500\u2003\u03bcm particles in direct contact with, or completely surrounded by, newly formed bone; smaller particles were also present in non\u2010mineralized tissue. In the case of BCP the bone\u2013graft substitute interface showed evidence of superficial disintegration of particles into individual grains. Median Ca\/P ratios (at.%), determined from &gt;200 discreet sites within residual graft particles and adjacent bone, were: DBB: 1.61 (confidence interval [CI] 1.59\u20131.64); BCP: 1.5 (CI 1.45\u20131.52); DBB\u2010augmented bone: 1.62 (CI 1.59\u20131.66); BCP\u2010augmented bone: 1.52 (CI 1.47\u20131.55); <jats:italic>P<\/jats:italic>=0.028 for DBB vs. BCP and DBB\u2010 vs. BCP\u2010augmented bone. The reduction in Ca\/P ratio for BCP over the healing period is consistent with the dissolution of \u03b2\u2010TCP and reprecipitation on the surface of calcium\u2010deficient hydroxyapatite.<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> The \u03b2\u2010TCP component of BCP may be gradually substituted by calcium\u2010deficient hydroxyapatite over the healing period. This process and superficial degranulation of BCP particles may influence the progress of resorption and healing.<\/jats:p><jats:p> <jats:bold>To cite this article:<\/jats:bold>\n          \u2028Lindgren C, Hallman M, Sennerby L, Sammons R. Back\u2010scattered electron imaging and elemental analysis of retrieved bone tissue following sinus augmentation with deproteinized bovine bone or biphasic calcium phosphate.\u2028<jats:italic>Clin. Oral Impl. Res<\/jats:italic>. <jats:bold>21<\/jats:bold>, 2010; 924\u2013930.\u2028doi: 10.1111\/j.1600\u20100501.2010.01933.x<\/jats:p>","DOI":"10.1111\/j.1600-0501.2010.01933.x","type":"journal-article","created":{"date-parts":[[2010,5,10]],"date-time":"2010-05-10T01:38:21Z","timestamp":1273455501000},"page":"924-930","source":"Crossref","is-referenced-by-count":31,"title":["Back\u2010scattered electron imaging and elemental analysis of retrieved bone tissue following sinus augmentation with deproteinized bovine bone or biphasic calcium phosphate"],"prefix":"10.1111","volume":"21","author":[{"given":"Christer","family":"Lindgren","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mats","family":"Hallman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Sennerby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Sammons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,8,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-83242008000100002"},{"key":"e_1_2_7_3_1","first-page":"49","article-title":"Which hard tissue augmentation techniques are the most successful in furnishing bony support for implant placement?","volume":"22","author":"Aghaloo T.L.","year":"2007","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_7_4_1","first-page":"395","article-title":"Efficacy of porous bovine bone mineral in various types of osseous deficiencies","volume":"21","author":"Artzi Z.","year":"2001","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940411300907"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9785(86)80084-9"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01565.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(98)00061-1"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.6.940"},{"key":"e_1_2_7_10_1","volume-title":"Structure and Chemistry of the Apatites and Other Calcium Orthophosphates. 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