{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:38:02Z","timestamp":1791171482997,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2012,8,15]],"date-time":"2012-08-15T00:00:00Z","timestamp":1344988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to evaluate the extent and quality of new bone 6\u00a0months after sinus lift with biphasic micro\u2010 and macroporous calcium phosphate combined with fibrin sealant (<jats:styled-content style=\"fixed-case\">MBCP\u2010FS<\/jats:styled-content>) and the 1\u2010year implant success rate in the augmented site.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">MBCP\u2010FS<\/jats:styled-content> was applied to one sinus in 96 subjects requiring augmentation for delayed dental implant placement. In subjects who required bilateral lifts (<jats:italic>N\u00a0<\/jats:italic>=\u00a033), the <jats:styled-content style=\"fixed-case\">MBCP\u2010FS<\/jats:styled-content> sinus was randomly selected; the contralateral sinus was grafted with autologous bone (mixed with Bio\u2010Oss when harvested bone volume was insufficient. Panoramic views were taken periodically prior to and up to 18\u00a0months post\u2010lift. Histomorphometric analysis was conducted on biopsies taken during implant placement 6\u00a0months after augmentation. Implant functionality and prosthesis success were assessed clinically 1\u00a0year after implant placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In <jats:styled-content style=\"fixed-case\">MBCP\u2010FS<\/jats:styled-content> sinuses, 20.6\u00a0\u00b1\u00a08.5% new, mainly lamellar bone was observed. Implants were placed as planned in 78\/85 evaluable subjects (91.8%) 6\u00a0months after sinus lift. Graft heights remained stable 1\u00a0year after placement; 94.7% (142\/150) of implants were functional. The amount and quality of new bone and implant success rates with <jats:styled-content style=\"fixed-case\">MBCP\u2010FS<\/jats:styled-content> were similar to autologous bone graft (mixed with Bio\u2010Oss in 30\/31 evaluable subjects). <jats:styled-content style=\"fixed-case\">MBCP\u2010FS<\/jats:styled-content> was safe and well\u2010tolerated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">MBCP\u2010FS<\/jats:styled-content> is safe and effective in sinus floor elevation for dental implant placement, supporting bone regeneration and with high 1\u2010year implant success rates similar to autologous bone mixed with Bio\u2010Oss.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-0501.2011.02275.x","type":"journal-article","created":{"date-parts":[[2012,8,15]],"date-time":"2012-08-15T06:44:20Z","timestamp":1345013060000},"page":"1112-1117","source":"Crossref","is-referenced-by-count":32,"title":["Bone formation with a biphasic calcium phosphate combined with fibrin sealant in maxillary sinus floor elevation for delayed dental implant"],"prefix":"10.1111","volume":"23","author":[{"given":"Wilfried","family":"Wagner","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery\/Plastic Surgery University Hospital Mainz Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Wiltfang","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery\/Plastic Surgery University of Kiel Kiel Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Pistner","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery \/ Plastic Surgery HELIOS Hospital Erfurt Erfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Yildirim","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics University of Aachen Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Ploder","sequence":"additional","affiliation":[{"name":"Baxter Innovations GmbH Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miranda","family":"Chapman","sequence":"additional","affiliation":[{"name":"Baxter Innovations GmbH Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Schiestl","sequence":"additional","affiliation":[{"name":"Baxter Innovations GmbH Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith","family":"Hantak","sequence":"additional","affiliation":[{"name":"Baxter Innovations GmbH Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,8,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022828606312"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940411300907"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200002000-00003"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2007.00050.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01565.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949210100808"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022842404495"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1982.tb00172.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1586\/17434440.2.1.87"},{"key":"e_1_2_7_11_1","first-page":"297","article-title":"Sinus lift with guided bone regeneration or anorganic bovine bone: 1\u2010year post\u2010loading results of a pilot randomized clinical trial","volume":"3","author":"Esposito M.","year":"2010","journal-title":"European Journal of Oral Implantology"},{"key":"e_1_2_7_12_1","first-page":"273","article-title":"Histomorphometric comparison of a biphasic bone ceramic to anorganic bovine bone for sinus augmentation: 6\u2010 to 8\u2010month postsurgical assessment of vital bone formation. 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