{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T02:48:41Z","timestamp":1785293321119,"version":"3.55.0"},"reference-count":55,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2011,11,22]],"date-time":"2011-11-22T00:00:00Z","timestamp":1321920000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to analyse the microarchitecture of bone in association with implant placement in young ectodermal dysplasia (<jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>) patients. The general hypothesis was that the structural and morphological features of bone microarchitecture are different between males and females, which may influence clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The bone harvesting is not additionally invasive, as the procedure was made at the time and site of implant placement. Twenty one samples (8 female, 13 male) were harvested from nine <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> participants whose age ranged between 14 and 21\u00a0years and specified by the site of harvesting. Micro\u2010<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> analysis at 5\u00a0\u00b5m resolution was conducted on each sample. Specialized <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> analysis of the three\u2010dimensional (<jats:styled-content style=\"fixed-case\">3\u2010D<\/jats:styled-content>) bone microstructure was made to compare structural parameters. In addition, two bone samples (one male, one female) were sent to the University of Michigan and analysed at 9\u00a0\u00b5m resolution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant difference was found between male and female samples. Bone analysis of particular sites revealed that bone\u2010specific surface (<jats:styled-content style=\"fixed-case\">BS<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">BV<\/jats:styled-content>) was found to be significantly higher in male than in female samples, whilst the mean values of 10 parameters, the grey scale value histograms and <jats:styled-content style=\"fixed-case\">3\u2010D<\/jats:styled-content> visualization showed that female samples had higher compact density than male samples.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Microstructural analyses indicated that female <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> bone was more compact and with greater trabecular connectedness than male bone. These features may enhance resistance to external force transfer of mastication compared with male bone. Further bone samples from other jaw bone areas will provide information on whether there are regional differences in jawbone quality and quantity, which may influence implant treatment outcomes, as well as follow\u2010up analyses of treatment outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-0501.2011.02303.x","type":"journal-article","created":{"date-parts":[[2011,11,23]],"date-time":"2011-11-23T02:48:46Z","timestamp":1322016526000},"page":"1275-1282","source":"Crossref","is-referenced-by-count":6,"title":["Bone microarchitecture at oral implant sites in ectodermal dysplasia (<scp>ED<\/scp>): a comparison between males and females"],"prefix":"10.1111","volume":"23","author":[{"given":"Patcharawan","family":"Silthampitag","sequence":"first","affiliation":[{"name":"Professorial Unit Faculty of Dentistry The University of Sydney Westmead Centre for Oral Health Westmead NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iven","family":"Klineberg","sequence":"additional","affiliation":[{"name":"Professorial Unit Faculty of Dentistry The University of Sydney Westmead Centre for Oral Health Westmead NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Austin","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Faculty of Dentistry The University of Sydney Westmead Centre for Oral Health Westmead NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan S.","family":"Jones","sequence":"additional","affiliation":[{"name":"Australian Centre for Microscopy &amp; Microanalysis The University of Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,11,22]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"347","article-title":"Long\u2010term follow\u2010up study of osseointegrated implants in the treatment of totally edentulous jaws","volume":"5","author":"Adell R.","year":"1990","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1988.59.5.287"},{"key":"e_1_2_7_4_1","first-page":"416","article-title":"Bone density assessments of dental implant sites: 2. 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