{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:16:41Z","timestamp":1793146601270,"version":"4.5.0"},"reference-count":48,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Inferior alveolar nerve (<jats:styled-content style=\"fixed-case\">IAN<\/jats:styled-content>) is the most commonly injured nerve (64.4%) during implant treatment. At present, no standardized protocol exists for clinicians to manage <jats:styled-content style=\"fixed-case\">IAN<\/jats:styled-content> injury related with implant surgery. Therefore, the purposes of the present article were to analyze the reasons for nerve injury and to propose guidelines in managing <jats:styled-content style=\"fixed-case\">IAN<\/jats:styled-content> injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Patients with <jats:styled-content style=\"fixed-case\">IAN<\/jats:styled-content> sensory disturbances after implant treatment were recruited for the study. Sixteen patients, eight men and eight women, with a mean age of 52.2\u00a0\u00b1\u00a08.1\u00a0years participated in this study. Patient examination, treatment, and <jats:styled-content style=\"fixed-case\">IAN<\/jats:styled-content> sensory function recovery monitoring were performed following six\u2010step <jats:styled-content style=\"fixed-case\">IAN<\/jats:styled-content> injury during dental implant surgery (<jats:styled-content style=\"fixed-case\">IANIDIS<\/jats:styled-content>) protocol. The control group was composed of 25 healthy volunteers who never had <jats:styled-content style=\"fixed-case\">IAN<\/jats:styled-content> sensory disturbances or any trauma in the maxillofacial region.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">IAN<\/jats:styled-content> sensory disturbances were scored as following: 5 (31.25%) had hyperalgesia and 11 (68.75%) expressed hypoalgesia. The mean asymmetry index (<jats:styled-content style=\"fixed-case\">AI<\/jats:styled-content>) was calculated for each patient and varied from 0.6 to 3.2. Overall, 31.3% of nerve injury patients were classified as mild, 31.3% as moderate, and remaining 37.5% as severe injury. All patients were successfully treated with proposed <jats:styled-content style=\"fixed-case\">IANIDIS<\/jats:styled-content> protocol.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The most frequent (50%) risk factor for <jats:styled-content style=\"fixed-case\">IAN<\/jats:styled-content> injury was intraoperative bleeding during bone preparation. The most common (56.3%) etiological risk factor of nerve injury was dental implant. A six\u2010step protocol aimed at managing patients with <jats:styled-content style=\"fixed-case\">IAN<\/jats:styled-content> injury, during dental implant surgery, was a useful tool that could provide successful treatment outcome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-0501.2011.02314.x","type":"journal-article","created":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T06:57:00Z","timestamp":1320130620000},"page":"183-190","source":"Crossref","is-referenced-by-count":77,"title":["Inferior alveolar nerve injury associated with implant surgery"],"prefix":"10.1111","volume":"24","author":[{"given":"Gintaras","family":"Juodzbalys","sequence":"first","affiliation":[{"name":"Department of Maxillofacial Surgery Lithuanian University of Health Sciences Kaunas Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hom\u2010Lay","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine School of Dentistry University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gintautas","family":"Sabalys","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Surgery Lithuanian University of Health Sciences Kaunas Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antanas","family":"Sidlauskas","sequence":"additional","affiliation":[{"name":"Clinic of Orthodontics Lithuanian University of Health Sciences Kaunas Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Galindo\u2010Moreno","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implant Dentistry School of Dentistry University of Granada Granada Spain"},{"name":"Department of Periodontics and Oral Medicine School of Dentistry University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-006-0065-0"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1563\/AAID-JOI-D-09-00059"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01138.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(99)90720-6"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.2009.00362.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2000.6974"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1563\/1548-1336(2002)028<0230:ISTMOS>2.3.CO;2"},{"key":"e_1_2_6_9_1","doi-asserted-by":"crossref","first-page":"344","DOI":"10.12968\/denu.1999.26.8.344","article-title":"Neurological complications of local anaesthetics in dentistry","volume":"26","author":"Crean S.J.","year":"1999","journal-title":"Dental Update"},{"key":"e_1_2_6_10_1","first-page":"462","article-title":"Sensory disturbances associated with implant surgery","volume":"11","author":"Dao T.T.","year":"1998","journal-title":"The International Journal of Prosthodontics"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3913(05)80154-4"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.id.0000190252.60779.ae"},{"key":"e_1_2_6_13_1","first-page":"674","article-title":"The prevalence of altered sensation associated with implant surgery","volume":"8","author":"Ellies L.G.","year":"1993","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.060197"},{"key":"e_1_2_6_15_1","first-page":"176","article-title":"Neuropathic complications of mandibular implant surgery: review and case presentations","volume":"15","author":"Gregg J.M.","year":"2000","journal-title":"Annals of the Royal Australasian College of Dental Surgeons"},{"key":"e_1_2_6_16_1","first-page":"866","article-title":"Influence of bone and dental implant parameters on stress distribution in the mandible: a finite element study","volume":"24","author":"Guan H.","year":"2009","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_17_1","first-page":"319","article-title":"A 21 year retrospective study of reports of paresthesia following local anesthetic administration","volume":"61","author":"Haas D.A.","year":"1995","journal-title":"Journal\/Canadian Dental Association. 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