{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:03:45Z","timestamp":1787015025713,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,3,16]],"date-time":"2012-03-16T00:00:00Z","timestamp":1331856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      The aim of this study was to perform an ultrastructural study of the bone\u2010to\u2010biomaterial interface and biomaterial mineral degradation in retrieved bone biopsies following maxillary sinus augmentation using bovine xenografts (Endobon\n                      <jats:sup>\u00ae<\/jats:sup>\n                      ) in 15 clinical cases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>\n                      Nine months after sinus lifting, bone cores were harvested from the maxillary sinus. The specimens were processed for observation under a scanning electron microscope with backscattered electron imaging (\n                      <jats:styled-content style=\"fixed-case\">SEM<\/jats:styled-content>\n                      \u2010\n                      <jats:styled-content style=\"fixed-case\">BSE<\/jats:styled-content>\n                      ). In addition, chemical analysis and elemental mapping of the mineral composition were generated using a microanalytical system based on energy\u2010dispersive\n                      <jats:styled-content style=\"fixed-case\">X<\/jats:styled-content>\n                      \u2010ray spectrometry (\n                      <jats:styled-content style=\"fixed-case\">EDX<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      No clinical complications occurred during surgery. Scanning electron microscopy revealed that newly formed bone was closely attached to the xenograft. Elemental analysis showed a significantly high\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:roman>Ca<\/jats:roman>\n                      <\/jats:styled-content>\n                      \/\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:roman>P<\/jats:roman>\n                      <\/jats:styled-content>\n                      ratio in the residual biomaterials (3.031\u00a0\u00b1\u00a00.104) compared with the interface (2.908\u00a0\u00b1\u00a00.115) and new bone (2.889\u00a0\u00b1\u00a00.113), which suggests that there may be a gradual diffusion of\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:roman>Ca<\/jats:roman>\n                      <\/jats:styled-content>\n                      ions from the biomaterial into the newly forming bone at the interface as part of the biomaterial's resorption process.\n                      <jats:styled-content style=\"fixed-case\">EDX<\/jats:styled-content>\n                      analysis of the residual bovine biomaterial showed particle categories with different mean\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:roman>Ca<\/jats:roman>\n                      <\/jats:styled-content>\n                      \/\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:roman>P<\/jats:roman>\n                      <\/jats:styled-content>\n                      ratios according to size, pointing to different stages of the resorption process.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The biomaterial proved to be biocompatible and osteoconductive when used as a bone substitute for maxillary sinus elevation. The grafting material used is not a completely resorbable material over the time period covered by this study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/j.1600-0501.2012.02439.x","type":"journal-article","created":{"date-parts":[[2012,3,16]],"date-time":"2012-03-16T00:10:35Z","timestamp":1331856635000},"page":"645-651","source":"Crossref","is-referenced-by-count":17,"title":["RETRACTED: Ultrastructural study by backscattered electron imaging and elemental microanalysis of biomaterial\u2010to\u2010bone interface and mineral degradation of bovine xenografts in maxillary sinus floor elevation"],"prefix":"10.1111","volume":"24","author":[{"given":"Mar\u00eda Piedad","family":"Ram\u00edrez\u2010Fern\u00e1ndez","sequence":"first","affiliation":[{"name":"Department of Implant Dentistry Faculty of Medicine and Dentistry University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis","family":"Calvo\u2010Guirado","sequence":"additional","affiliation":[{"name":"Department of Implant Dentistry Faculty of Medicine and Dentistry University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael Arcesio","family":"Delgado\u2010Ruiz","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Faculty of Medicine and Dentistry University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Eduardo","family":"Mat\u00e9\u2010S\u00e1nchez del Val","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Faculty of Medicine and Dentistry University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Negri","sequence":"additional","affiliation":[{"name":"Department of Implant Dentistry Faculty of Medicine and Dentistry University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Pe\u00f1arrocha Diago","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery Faculty of Medicine and Dentistry University of Valencia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,3,16]]},"reference":[{"issue":"1","key":"e_1_2_6_2_1","first-page":"49","article-title":"Which hard tissue augmentation techniques are the most successful in furnishing bony support for the implant placement?","volume":"22","author":"Aghaloo T.L.","year":"2007","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_3_1","first-page":"351","article-title":"Clinical and histological study of a xenogenic bone substitute used as a filler in post\u2010extractive alveolus","volume":"54","author":"Arcuri C.","year":"2005","journal-title":"Minerva Stomatologica"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1054\/jhsb.2001.0686"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(00)00015-6"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/088532829000500105"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001130100303"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2011.02193.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01565.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2009.00203.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1632619"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2011.02288.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004020050426"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004020000194"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1018500309969"},{"key":"e_1_2_6_16_1","first-page":"90","article-title":"Reconstruction of severely resorbed alveolar ridge crests with dental implants using a bovine bone mineral for augmentation","volume":"16","author":"Hising P.","year":"2001","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_17_1","first-page":"1051","article-title":"Bone ingrowth into porous coated canine total hip replacements. 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