{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:24:01Z","timestamp":1790731441553,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,3,29]],"date-time":"2012-03-29T00:00:00Z","timestamp":1332979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the influence of a sub\u2010epithelial connective tissue graft placed at the buccal aspect of implants installed immediately after tooth extraction on the dimensional changes of hard and soft tissues.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>In six Labrador dogs a bilateral partial\u2010 thickness dissection was made buccal to the second mandibular premolar. At the lingual aspect, full\u2010thickness flaps were elevated. The teeth were extracted and implants installed immediately into the distal socket. A connective tissue graft was obtained from the palate and applied to the buccal aspect of the test sites, whereas contra\u2010laterally, no graft was applied. The flaps were sutured to allow a non\u2010submerged installation. After 4\u00a0months of healing, the animals were sacrificed, ground sections were obtained and histomorphometric analyses were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After 4\u00a0months of healing, all implants were integrated (<jats:italic>n<\/jats:italic>\u00a0=\u00a06). Both at the test and at the control sites bone resorption occurred: 1.6\u00a0mm and 2.1\u00a0mm, respectively. The difference was not statistically significant. The coronal aspect of the peri\u2010implant soft tissue was wider and located more coronally at the test compared with the control sites. The differences were statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The application of a connective tissue graft placed at the buccal aspect of the bony wall at implants installed immediately after tooth extraction yielded a minimal preservation of the hard tissues. The peri\u2010implant mucosa, however, was significantly thicker and more coronally positioned at the test compared with the control sites.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-0501.2012.02450.x","type":"journal-article","created":{"date-parts":[[2012,3,31]],"date-time":"2012-03-31T16:39:46Z","timestamp":1333211986000},"page":"50-56","source":"Crossref","is-referenced-by-count":24,"title":["Connective tissue grafts in conjunction with implants installed immediately into extraction sockets. An experimental study in dogs"],"prefix":"10.1111","volume":"24","author":[{"given":"Marco","family":"Caneva","sequence":"first","affiliation":[{"name":"UNESP \u2013Universidade Estadual Paulista, Ara\u00e7atuba Dental School Aracatuba Brazil"},{"name":"ARDEC, Ariminum Odontologica Rimini Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Botticelli","sequence":"additional","affiliation":[{"name":"ARDEC, Ariminum Odontologica Rimini Italy"},{"name":"Faculty of Dentistry University of Medical Science La Habana Cuba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Vigan\u00f2","sequence":"additional","affiliation":[{"name":"Faculdade de Odontologia de Ara\u00e7atuba UNESP \u2013Universidade Estadual Paulista Paulista Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Morelli","sequence":"additional","affiliation":[{"name":"Faculdade de Odontologia de Ara\u00e7atuba UNESP \u2013Universidade Estadual Paulista Paulista Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Rea","sequence":"additional","affiliation":[{"name":"Faculdade de Odontologia de Ara\u00e7atuba UNESP \u2013Universidade Estadual Paulista Paulista Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niklaus P.","family":"Lang","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry University of Medical Science La Habana 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