{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T10:51:47Z","timestamp":1759229507560},"reference-count":14,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T00:00:00Z","timestamp":1335744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to report on the failure rates of two distinct dental implant systems in a clinical practice setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Date of implant placement and loss were entered prospectively in a data registry system. Failure rates of two commercially pure titanium implants, one with a porous oxydized surface (<jats:styled-content style=\"fixed-case\">POS<\/jats:styled-content>) and the other with a chemically altered surface (<jats:styled-content style=\"fixed-case\">CAS<\/jats:styled-content>), were assessed using a quality control chart and survival analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 860 <jats:styled-content style=\"fixed-case\">POS<\/jats:styled-content> and 759 <jats:styled-content style=\"fixed-case\">CAS<\/jats:styled-content> implants were placed. A warning of an increased failure rate of the <jats:styled-content style=\"fixed-case\">CAS<\/jats:styled-content> implant was identified by means of the quality control chart. Survival analyses indicated that the <jats:styled-content style=\"fixed-case\">CAS<\/jats:styled-content> implant failure rate was twice that of the <jats:styled-content style=\"fixed-case\">POS<\/jats:styled-content> implant (Hazard Ratio: 2.08; 95% CI: 1.33\u20133.28, <jats:italic>P<\/jats:italic>\u2010value\u00a0&lt;\u00a00.0012). After adjusting for alternative explanations, the <jats:styled-content style=\"fixed-case\">CAS<\/jats:styled-content> implant remained associated with a 95% increased failure rate (95% CI: 1.14\u20133.35; <jats:italic>P<\/jats:italic>\u2010value\u00a0=\u00a00.0146). Abandoning the <jats:styled-content style=\"fixed-case\">CAS<\/jats:styled-content> implant and returning to a <jats:styled-content style=\"fixed-case\">POS<\/jats:styled-content> implant was associated with a non\u2010significant 64% drop in the implant failure rate within less than a year (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>: 0.36; 95% CI: 0.12\u20131.14; <jats:italic>P<\/jats:italic>\u2010value\u00a0&lt;\u00a00.0826).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The difference between a 4% failure rate with the <jats:styled-content style=\"fixed-case\">POS<\/jats:styled-content> implant and an 8% failure with the <jats:styled-content style=\"fixed-case\">CAS<\/jats:styled-content> implant appears inconsistent with the assumption of substantial equivalence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-0501.2012.02477.x","type":"journal-article","created":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T06:52:43Z","timestamp":1335768763000},"page":"725-729","source":"Crossref","is-referenced-by-count":5,"title":["Monitoring Failure Rates of Commercial Implant Brands; Substantial Equivalence in Question?"],"prefix":"10.1111","volume":"24","author":[{"given":"Philippe","family":"Hujoel","sequence":"first","affiliation":[{"name":"School of Dentistry, UW Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Becker","sequence":"additional","affiliation":[{"name":"Tucson AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burton","family":"Becker","sequence":"additional","affiliation":[{"name":"Tucson AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,4,30]]},"reference":[{"key":"e_1_2_7_2_1","article-title":"Prospective clinical trial evaluating a new implant system for implant survival, implant stability and radiographic bone changes","author":"Becker W.","year":"2011","journal-title":"Clinical Implant Dentistry and Related Research"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2005.tb00071.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1972.tb00899.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6418"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzq037"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpa.2011.02.010"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1213\/ANE.0b013e3181d00c74","article-title":"A surgical site infection cluster: the process and outcome of an investigation\u2013the impact of an alcohol\u2010based surgical antisepsis product and human behavior","volume":"110","author":"Haessler S.","year":"2010","journal-title":"Anesthesia & Analgesia"},{"key":"e_1_2_7_9_1","volume-title":"Medical Devices and the Public's Health: The fda 510(k) Clearance Process at 35\u00a0Years, 1\u20104","author":"Institute of Medicine of the National Academies","year":"2011"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-015-7983-4_14"},{"key":"e_1_2_7_11_1","first-page":"199","volume-title":"Tissue\u2010Integrated Prostheses: Osseointegration in Clinical Dentistry","author":"Lekholm U.","year":"1985"},{"key":"e_1_2_7_12_1","volume-title":"Quality Control Charts","author":"Pearson E.S.","year":"1942"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0010274"},{"key":"e_1_2_7_14_1","volume-title":"Sas\/stat\u00ae 9.3 User's Guide., Cary","author":"SAS Institute Inc","year":"2011"},{"key":"e_1_2_7_15_1","volume-title":"Die aetiologie, der begriff und die prophylaxis des kindbettfiebers","author":"Semmelweis I.F","year":"1861"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0501.2012.02477.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0501.2012.02477.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T08:53:38Z","timestamp":1697619218000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0501.2012.02477.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,30]]},"references-count":14,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1111\/j.1600-0501.2012.02477.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0501.2012.02477.x","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,30]]}}}