{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T15:16:29Z","timestamp":1782227789072,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,6,15]],"date-time":"2012-06-15T00:00:00Z","timestamp":1339718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to compare the clinical outcomes after 2\u00a0years with bone level implants placed to restore a single missing teeth that needed simultaneous augmentation and were treated with a transmucosal or submerged approach.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study analyzed a subset of patients included in an ongoing prospective multicenter randomized clinical trial (<jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>) involving12 centers where patients were to be followed\u2010up to 5\u00a0years after loading. Of the 120 implants that were placed in the original study, and randomly assigned to submerged or non\u2010submerged healing, 52 needed simultaneous augmentation (28 women patients and 24 men patients, between 23 and 78\u00a0years of age). Twenty\u2010seven of them received implants with submerged healing (<jats:styled-content style=\"fixed-case\">AuS<\/jats:styled-content>), while in 25 patients the implants were inserted with a non\u2010submerged protocol (<jats:styled-content style=\"fixed-case\">AuNS<\/jats:styled-content>).<\/jats:p><jats:p>At the 2\u2010year follow\u2010up visit, radiographic crestal bone level changes were recorded as well as soft tissue parameters included Pocket probing depth (<jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content>), bleeding on probing (<jats:styled-content style=\"fixed-case\">BoP<\/jats:styled-content>) and clinical attachment level (<jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content>) at teeth adjacent to the implant site.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After 2 years a small amount of bone resorption was found in both groups (0.37\u00a0\u00b1\u00a00.49\u00a0mm in the AuS group and 0.54\u00a0\u00b1\u00a00.76 in the AuNS group; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><jats:p>There was no statistically significant difference between <jats:styled-content style=\"fixed-case\">AuS<\/jats:styled-content> Group and <jats:styled-content style=\"fixed-case\">AuNS<\/jats:styled-content> group for <jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content> (2.5 vs. 2.4\u00a0mm), <jats:styled-content style=\"fixed-case\">BOP<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">BOP<\/jats:styled-content> + sites: 8.8% vs. 11.5%) and <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content> (2.8 vs. 2.4\u00a0mm) at the 2\u2010year follow\u2010up visit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>When a single implant is placed in the aesthetic zone in conjunction with bone augmentation for a moderate peri\u2010implant defect, submerged and transmucosal healing determine similar outcome, hence there is no need to submerge an implant in this given clinical situation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-0501.2012.02521.x","type":"journal-article","created":{"date-parts":[[2012,6,15]],"date-time":"2012-06-15T05:16:12Z","timestamp":1339737372000},"page":"1130-1136","source":"Crossref","is-referenced-by-count":15,"title":["Implant\u2010supported single tooth restoration in the aesthetic zone: transmucosal and submerged healing provide similar outcome when simultaneous bone augmentation is needed"],"prefix":"10.1111","volume":"24","author":[{"given":"Luca","family":"Cordaro","sequence":"first","affiliation":[{"name":"Department of Periodontology and Prosthodontics Eastman Dental Hospital  Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferruccio","family":"Torsello","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Prosthodontics Eastman Dental Hospital  Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Chen","sequence":"additional","affiliation":[{"name":"Periodontics, School of Dental Science University of Melbourne  Parkville Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Ganeles","sequence":"additional","affiliation":[{"name":"Department of Periodontics Nova Southeastern University  Ft. Lauderdale FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urs","family":"Br\u00e4gger","sequence":"additional","affiliation":[{"name":"Division of Fixed Prosthodontics University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"H\u00e4mmerle","sequence":"additional","affiliation":[{"name":"Clinic for Fixed and Removable Prosthodontics and Dental Materials School of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,6,15]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"49","article-title":"Which hard tissue augmentation techniques are the most successful in furnishing bony support for implant placement?","volume":"22","author":"Aghaloo T.L.","year":"2007","journal-title":"International Journal of Oral & Maxillofacial 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