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The aim of this study was to develop a simple screening methodology for the evaluation of the osteoconductive potential of various bone graft materials prior to clinical use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Materials tested were Bio\u2010Oss, Bi\u2010Ostetic, OraGraft, and ProOsteon. These Simple and composite bone substitutes were embedded with osteoprogenitor cells derived from either the human maxillary sinus schneiderian membrane (h<jats:styled-content style=\"fixed-case\">MSSM<\/jats:styled-content>) or from maxillary tuberosity bone marrow and then monitored both <jats:italic>in vitro<\/jats:italic> and <jats:italic>in vivo<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cell adherence and proliferation was most pronounced in OraGraft, followed by ProOsteon. <jats:italic>In vivo<\/jats:italic> bone formation, within the bone graft, was also observed, with most marked results in OraGraft and ProOsteon grafts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The proposed osteoconductivity testing method proved simple, informative, and reliable for the purpose of screening candidate biomaterials for sinus lifting or sinus 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