{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T09:57:05Z","timestamp":1780653425089,"version":"3.54.1"},"reference-count":40,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2004,6,10]],"date-time":"2004-06-10T00:00:00Z","timestamp":1086825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2004,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim: <\/jats:bold> The aim of this controlled, parallel design clinical study was to compare the healing of intrabony periodontal defects following treatment with access flap surgery with and without debridement with an Er:YAG laser.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> Twenty\u2010three patients each of whom exhibited one deep intrabony defect were randomly treated with either access flap surgery followed by root surface and defect debridement using an Er:YAG laser (KEY3\u00ae) (160\u2003mJ, 10\u2003Hz) (test), or with access flap surgery followed by root surface and defect debridement using hand and ultrasonic instruments (control). The following clinical parameters were recorded at baseline and at 6 months: plaque index; gingival index; bleeding on probing; probing depth (PD); gingival recession; and clinical attachment level (CAL). The primary outcome variable was CAL. No statistically significant differences between the groups were found at baseline.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> No serious adverse events were observed after any of the treatments. The results have shown that in the test group the PD decreased from 7.8\u00b11.3 to 4.1\u00b11.3\u2003mm (<jats:italic>p<\/jats:italic>&lt;0.001) and the CAL changed from 9.8\u00b12.9 to 7.2\u00b12.5\u2003mm (<jats:italic>p<\/jats:italic>&lt;0.001). In the control group the PD decreased from 7.8\u00b10.8 to 4.6\u00b11.6\u2003mm (<jats:italic>p<\/jats:italic>&lt;0.001) and the CAL changed from 9.2\u00b11.2 to 7.7\u00b11.6\u2003mm (<jats:italic>p<\/jats:italic>&lt;0.01). The test group displayed a higher tendency for CAL gain, although this tendency did not prove to be statistically significant.<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> Within the limits of the present study, it can be concluded that: (i) at 6 months following treatment both therapies led to significant improvements of the investigated clinical parameters, and (ii) an Er:YAG laser may represent a suitable alternative for defect and root surface debridement in conjuction with periodontal surgery.<\/jats:p>","DOI":"10.1111\/j.1600-051x.2004.00525.x","type":"journal-article","created":{"date-parts":[[2004,7,15]],"date-time":"2004-07-15T09:56:32Z","timestamp":1089885392000},"page":"604-608","source":"Crossref","is-referenced-by-count":62,"title":["Healing of intrabony defects following surgical treatment with or without an Er:YAG laser"],"prefix":"10.1111","volume":"31","author":[{"given":"Anton","family":"Sculean","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Berakdar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Windisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole B.","family":"Arweiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg E.","family":"Romanos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,7,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9101(1996)19:2<190::AID-LSM11>3.0.CO;2-B"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.12.1097"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2002.73.4.370"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.1995.tb00005.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1997.tb00225.x"},{"key":"e_1_2_5_7_1","first-page":"242","article-title":"Smear layer formed by different root planing modalities and its removal by an ethylenediaminetetraacetic acid gel preparation","volume":"17","author":"Bloml\u00f6f J. P.","year":"1997","journal-title":"International Journal of Periodontics and Restorative Dentistry"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2000.027012889.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.8.763"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.8.701"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1998.tb02402.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1902\/jop.1996.67.3.217","article-title":"Periodontal regeneration of human intrabony defects with bioresorbable membranes A controlled clinical trial","volume":"67","author":"Cortellini P.","year":"1996","journal-title":"Journal of Periodontology"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2002.290111.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.2.147"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028003220.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1998.69.5.521"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1997.tb00235.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.2.93"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1089\/104454702753768034"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1999.70.11.1276"},{"key":"e_1_2_5_21_1","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1902\/jop.1967.38.6.610","article-title":"The gingival index, the plaque index and the retention index systems","volume":"38","author":"L\u00f6e H.","year":"1967","journal-title":"Journal of Periodontology"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9101(1998)22:5<302::AID-LSM7>3.0.CO;2-T"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1986.57.2.69"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1984.55.8.443"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1987.tb01573.x"},{"key":"e_1_2_5_26_1","first-page":"496","article-title":"Root instrumentation with an erbium:yttrium\u2010aluminum\u2010garnet laser","volume":"33","author":"Rossa C. J.","year":"2002","journal-title":"Quintessence International"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0765.2002.00657.x"},{"key":"e_1_2_5_28_1","first-page":"83","article-title":"Changes in root surface morphology and fibroblast adherence after Er:YAG laser irradiation","volume":"2","author":"Schoop U.","year":"2002","journal-title":"Journal of Oral Laser Applications"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.300105.x"},{"key":"e_1_2_5_30_1","first-page":"329","article-title":"Nonsurgical periodontal treatment with an Er:YAG laser (in German)","volume":"4","author":"Schwarz F.","year":"2000","journal-title":"Parodontologie"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.5.590"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.10179"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.00412.x"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.3.361"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028005397.x"},{"key":"e_1_2_5_36_1","first-page":"1009","article-title":"Effects of irradiation of Er:YAG laser on quantity of endotoxin and microhardness of surface in exposed root after removal of calculus","volume":"41","author":"Sugi D.","year":"1998","journal-title":"Japanese Journal of Conservative Dentistry"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.4.297"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9101(1996)18:2<150::AID-LSM4>3.0.CO;2-R"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1089\/clm.1996.14.67"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1995.66.12.1032"},{"key":"e_1_2_5_41_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.12.1151"}],"container-title":["Journal of Clinical Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-051X.2004.00525.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-051X.2004.00525.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T02:19:26Z","timestamp":1697422766000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-051X.2004.00525.x"}},"subtitle":["A pilot study"],"short-title":[],"issued":{"date-parts":[[2004,7,15]]},"references-count":40,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2004,8]]}},"alternative-id":["10.1111\/j.1600-051X.2004.00525.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-051x.2004.00525.x","archive":["Portico"],"relation":{},"ISSN":["0303-6979","1600-051X"],"issn-type":[{"value":"0303-6979","type":"print"},{"value":"1600-051X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,7,15]]}}}