{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T18:32:50Z","timestamp":1762540370709},"reference-count":9,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,2,20]],"date-time":"2006-02-20T00:00:00Z","timestamp":1140393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim: <\/jats:bold> To explore the possibility of using plaque weight rather than plaque index as a more objective, clinical outcome measure in periodontal clinical trials.<\/jats:p><jats:p><jats:bold>Materials and methods: <\/jats:bold> The study initially recruited 12 healthy volunteers who abstained from tooth cleaning for 24\u2003h on each of the three occasions and then for 48\u2003h on each of a further three occasions to accumulate plaque. On a further three visits, the subjects abstained from tooth cleaning for 24\u2003h and then brushed with a powered toothbrush for 2\u2003min. A split\u2010mouth design with target teeth was adopted and plaque was first scored separately on each side of the mouth using the Turesky modification of the Quigley and Hein plaque index. Post\u2010brushing residual plaque was also scored after tooth cleaning. Inter\u2010proximal plaque was dried, removed, pooled and weighed: on one side of the mouth from the entire inter\u2010proximal surfaces; and from beneath the contact points on the contra\u2010lateral side.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Discriminant validity showed the index to have an advantage over weight in discerning between 24\u2010 and 48\u2010h plaque deposits, and between 24\u2010h plaque and post\u2010brushing plaque. Test\u2010retest validity confirmed that for repeated plaque growth, variability within subjects was greater than the variability between subjects. There was an association between plaque weight and plaque index although the regression lines were non\u2010linear.<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> There appears to be no significant advantage in using plaque weight in periodontal clinical trials.<\/jats:p>","DOI":"10.1111\/j.1600-051x.2006.00877.x","type":"journal-article","created":{"date-parts":[[2006,2,20]],"date-time":"2006-02-20T15:01:50Z","timestamp":1140447710000},"page":"172-176","source":"Crossref","is-referenced-by-count":18,"title":["Measuring plaque in clinical trials: index or weight?"],"prefix":"10.1111","volume":"33","author":[{"given":"G. I.","family":"McCracken","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. M.","family":"Preshaw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. N.","family":"Steen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Swan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"DeJager","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. A.","family":"Heasman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,2,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1964.35.3.202"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00610.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.1999.260701.x"},{"key":"e_1_2_8_5_1","first-page":"384","article-title":"Conference on clinical trials in periodontal diseases","volume":"13","author":"Goodson J. 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