{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T07:21:32Z","timestamp":1784791292865,"version":"3.55.0"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,2,20]],"date-time":"2006-02-20T00:00:00Z","timestamp":1140393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aims: <\/jats:bold> The objective of this study was to characterize the inhibitory effects of <jats:italic>Weissella cibaria<\/jats:italic> isolates on volatile sulphur compounds (VSC) production both in vitro and in vivo.<\/jats:p><jats:p><jats:bold>Material and Methods: <\/jats:bold> We isolated and identified three hydrogen peroxide\u2010generating lactobacilli from children's saliva, and assessed their inhibitory effects on VSC production and <jats:italic>Fusobacterium nucleatum<\/jats:italic> proliferation. Clinical studies were conducted with 46 subjects in order to measure the VSC of their mouth air.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> These lactobacilli were identified as <jats:italic>W. cibaria<\/jats:italic>. These isolates inhibited the production of VSC by <jats:italic>F. nucleatum<\/jats:italic> (<jats:italic>p<\/jats:italic>&lt;0.05). The concentration of <jats:italic>F. nucleatum<\/jats:italic> was decreased by 5\u2010log cycles as a result of exposure to the <jats:italic>W. cibaria<\/jats:italic> strains (<jats:italic>p<\/jats:italic>&lt;0.05), whereas the catalase\u2010treated <jats:italic>W. cibaria<\/jats:italic> cultures exerted no evident inhibitory effects on <jats:italic>F. nucleatum<\/jats:italic> replication. In the clinical studies, gargling with one isolate resulted in a significant reduction in the levels of H<jats:sub>2<\/jats:sub>S and CH<jats:sub>3<\/jats:sub>SH by approximately 48.2% (<jats:italic>p<\/jats:italic>&lt;0.01) and 59.4% (<jats:italic>p<\/jats:italic>&lt;0.05), respectively.<\/jats:p><jats:p><jats:bold>Conclusions: <\/jats:bold> These results indicate that <jats:italic>W. cibaria<\/jats:italic> isolates possess the ability to inhibit VSC production under both in vitro and in vivo conditions, demonstrating that they bear the potential for development into novel probiotics for use in the oral cavity.<\/jats:p>","DOI":"10.1111\/j.1600-051x.2006.00893.x","type":"journal-article","created":{"date-parts":[[2006,2,20]],"date-time":"2006-02-20T15:01:50Z","timestamp":1140447710000},"page":"226-232","source":"Crossref","is-referenced-by-count":125,"title":["Inhibitory effect of <i>Weissella cibaria<\/i> isolates on the production of volatile sulphur compounds"],"prefix":"10.1111","volume":"33","author":[{"given":"Mi\u2010Sun","family":"Kang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung\u2010Gook","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun\u2010Chul","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong\u2010Suk","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,2,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2672.1998.00480.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000016430"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-52-1-141"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1128\/jb.128.2.616-622.1976","article-title":"Arginine catabolism by Treponema denticola","volume":"128","author":"Blakemore R. 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