{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T16:32:04Z","timestamp":1789576324038,"version":"build-2803163510"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,4,7]],"date-time":"2006-04-07T00:00:00Z","timestamp":1144368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2006,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim: <\/jats:bold> The present study aimed to evaluate if the oral cavity of chronic periodontitis patients can harbor <jats:italic>Helicobacter pylori<\/jats:italic> after systemic eradication therapy.<\/jats:p><jats:p><jats:bold>Materials and Methods: <\/jats:bold> Samples of 30 patients (15 with gingivitis and 15 with chronic periodontitis) positive for <jats:italic>H. pylori<\/jats:italic> in the stomach were evaluated. Samples were collected 3 months after triple systemic antibiotic therapy from saliva, microbiota from the dorsum of the tongue, supra\u2010 and sub\u2010gingival plaque as well as gastric biopsies. DNA of each sample was extracted by the boiling method and used as a template in polymerase chain reaction with the primers JW22\/23.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Eighteen patients (60%) harboured <jats:italic>H. pylori<\/jats:italic> in their mouths. Five patients (16.6%) were positive in saliva, two (6.6%) on the dorsum of the tongue, nine (30%) in supra\u2010gingival plaque, 14 (46.6%) in sub\u2010gingival plaque and three (10%) in the stomach. There was no statistically significant difference between study groups.<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> Eradication of <jats:italic>H. pylori<\/jats:italic> after therapy was more effective for the stomach than for the mouth (<jats:italic>p<\/jats:italic>&lt;0.001). Mouths of patients with gingivitis or with chronic periodontitis, who are positive for <jats:italic>H. pylori<\/jats:italic> in their stomachs, may be considered as reservoirs of these bacteria.<\/jats:p>","DOI":"10.1111\/j.1600-051x.2006.00915.x","type":"journal-article","created":{"date-parts":[[2006,4,7]],"date-time":"2006-04-07T07:57:35Z","timestamp":1144396655000},"page":"329-333","source":"Crossref","is-referenced-by-count":74,"title":["Persistence of <i>Helicobacter pylori<\/i> in the oral cavity after systemic eradication therapy"],"prefix":"10.1111","volume":"33","author":[{"given":"E. C. E.","family":"Gebara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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