{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T20:09:02Z","timestamp":1788206942957,"version":"build-2803163510"},"reference-count":48,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2006,7,17]],"date-time":"2006-07-17T00:00:00Z","timestamp":1153094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective: <\/jats:bold> The aim of the present study was to evaluate non\u2010submerged and submerged healing of ligature induced peri\u2010implantitis in dogs.<\/jats:p><jats:p><jats:bold>Material and Methods: <\/jats:bold> Peri\u2010implantitis was induced by ligature placement in five beagle dogs (<jats:italic>n<\/jats:italic>=30 implants). The defects were randomly and equally allocated in a split\u2010mouth design to either closed treatment+non\u2010submerged healing (CNS), or open treatment+submerged healing (OS) using an Er:YAG laser (ERL), an ultrasonic device (VUS), or plastic curettes+local application of metronidazole gel (PCM), respectively. The animals were sacrificed after 3 months. Clinical, radiological and histological (e.g. new bone\u2010to\u2010implant contact (BIC)) parameters were assessed.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> All treatment procedures resulted in statistically significant improvements of all clinical parameters at both CNS and OS implants. Radiological improvements were merely observed at OS implants. Histomorphometrical analysis revealed that all CNS implants exhibited comparable low amounts of new BIC (1.0\u20131.2%), while mean BIC was statistically significant higher in the respective OS groups [ERL (44.8%), PCM (14.8%), VUS (8.7%)].<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> Within the limits of the present study, it was concluded that (i) OS improved the outcome of treatment in comparison with CNS and (ii) ERL seemed to be more suitable to promote re\u2010osseointegration than PCM and VUS.<\/jats:p>","DOI":"10.1111\/j.1600-051x.2006.00956.x","type":"journal-article","created":{"date-parts":[[2006,7,17]],"date-time":"2006-07-17T13:54:37Z","timestamp":1153144477000},"page":"584-595","source":"Crossref","is-referenced-by-count":141,"title":["Influence of different treatment approaches on non\u2010submerged and submerged healing of ligature induced peri\u2010implantitis lesions: an experimental study in dogs"],"prefix":"10.1111","volume":"33","author":[{"given":"Frank","family":"Schwarz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren","family":"Jepsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Herten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Sager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Rothamel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"365","volume-title":"Proceedings of the 1st European Workshop on Periodontology","author":"Albrektsson T.","year":"1994"},{"key":"e_1_2_7_3_1","first-page":"11","article-title":"Microbial aspects of failing osseointegrated dental implants in humans","volume":"10","author":"Alcoforado G. A.","year":"1991","journal-title":"Journal de Parodontolgie"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1998.69.8.857"},{"key":"e_1_2_7_5_1","first-page":"9","article-title":"Implant surface preparation","volume":"3","author":"Baier R. E.","year":"1988","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_7_6_1","first-page":"533","article-title":"Experimentally induced peri\u2010implantitis","volume":"15","author":"Baron M.","year":"2000","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_7_7_1","first-page":"31","article-title":"Clinical and microbiologic findings that may contribute to dental implant failure","volume":"5","author":"Becker W.","year":"1990","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.2004.00768.x"},{"key":"e_1_2_7_9_1","first-page":"659","article-title":"Peri\u2010implant care of ailing implants with the carbon dioxide laser","volume":"16","author":"Deppe H.","year":"2001","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0344-0338(85)80209-0"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070404.x"},{"key":"e_1_2_7_12_1","first-page":"1","article-title":"The vector method","volume":"1","author":"Hahn R.","year":"2000","journal-title":"Parodontologie"},{"key":"e_1_2_7_13_1","first-page":"168","article-title":"Treatment of peri\u2010implantitis using guided bone regeneration and bone grafts, alone or in combination, in beagle dogs. Part 2","volume":"12","author":"H\u00fcrzeler M. B.","year":"1997","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01141.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2004.01056.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1993.040101.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1994.050401.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1999.100501.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.10.1415"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1992.030102.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1995.tb00180.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1089\/10445470360516680"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1988.tb00095.x"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2001.012004287.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1987.tb00298.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2000.tb00117.x"},{"key":"e_1_2_7_27_1","first-page":"78","article-title":"Effects of an air\u2010powder abrasive system on plasma\u2010sprayed titanium implant surfaces","volume":"15","author":"Parham P. L. Jr.","year":"1989","journal-title":"Journal of Oral Implantology"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1999.100302.x"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070410.x"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2004.tb00039.x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1991.020304.x"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.00296.x"},{"key":"e_1_2_7_33_1","first-page":"1","volume-title":"Methods of Calcified Tissue Preparation","author":"Schenk R. K.","year":"1984"},{"key":"e_1_2_7_34_1","first-page":"140","article-title":"Surgical treatment of peri\u2010implantitis","volume":"19","author":"Schou S.","year":"2004","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2003.00911.x"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2003.00912.x"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2002.130201.x"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2003.120910.x"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1993.040102.x"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.30628"},{"key":"e_1_2_7_41_1","first-page":"660","article-title":"Influence of an Er","volume":"113","author":"Schwarz F.","year":"2003","journal-title":"Schweizer Monatsschrift Zahnmedizin"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0905-7161.2003.00954.x"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-005-0305-8"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2004.01051.x"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1993.040103.x"},{"key":"e_1_2_7_46_1","first-page":"203","article-title":"Bone regeneration after peri\u2010implant care with the CO2 laser","volume":"20","author":"St\u00fcbinger S.","year":"2005","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_7_47_1","first-page":"64","article-title":"Subcutaneous emphysema of the oral floor during cleaning of a bridge fixed on an IMZ implant. Case report","volume":"46","author":"Van de Velde E.","year":"1991","journal-title":"Revue Belge de Medicine Dentaire"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1999.100205.x"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00567.x"}],"container-title":["Journal of Clinical Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-051X.2006.00956.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-051X.2006.00956.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T20:48:58Z","timestamp":1697057338000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-051X.2006.00956.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7,17]]},"references-count":48,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["10.1111\/j.1600-051X.2006.00956.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-051x.2006.00956.x","archive":["Portico"],"relation":{},"ISSN":["0303-6979","1600-051X"],"issn-type":[{"value":"0303-6979","type":"print"},{"value":"1600-051X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,7,17]]}}}