{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T16:22:34Z","timestamp":1777306954628,"version":"3.51.4"},"reference-count":50,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2006,8,3]],"date-time":"2006-08-03T00:00:00Z","timestamp":1154563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim: <\/jats:bold> The aim of this report was to assess the strength and influence of periodontitis as a possible risk factor for pre\u2010term birth (PTB) in a cohort of 81 primiparous Croatian mothers aged 18\u201339 years.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> PTB cases (<jats:italic>n<\/jats:italic>=17; mean age 25\u00b12.9 years; age range 20\u201333 years) were defined as spontaneous delivery after less than 37 completed weeks of gestation that were followed by spontaneous labour or spontaneous rupture of membranes. Controls (full\u2010time births) were normal births at or after 37 weeks of gestation (<jats:italic>n<\/jats:italic>=64; mean age 25\u00b12.9 years; age range 19\u201339 years). Information on known risk factors and obstetric factors included the current pregnancy history, maternal age at delivery, pre\u2010natal care, nutritional status, tobacco use, alcohol use, genitourinary infections, vaginosis, gestational age, and birth weight. Full\u2010mouth periodontal examination was performed on all mothers within 2 days of delivery.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> PTB cases had significantly worse periodontal status than controls (<jats:italic>p<\/jats:italic>=0.008). Multivariate logistic regression model, after controlling for other risk factors, demonstrated that periodontal disease is a significant independent risk factor for PTB, with an adjusted odds ratio of 8.13 for the PTB group (95% confidence interval 2.73\u201345.9).<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> Periodontal disease represents a strong, independent, and clinically significant risk factor for PTB in the studied cohort. There are strong indicators that periodontal therapy should form a part of preventive prenatal care in Croatia.<\/jats:p>","DOI":"10.1111\/j.1600-051x.2006.00977.x","type":"journal-article","created":{"date-parts":[[2006,8,3]],"date-time":"2006-08-03T10:36:10Z","timestamp":1154601370000},"page":"710-716","source":"Crossref","is-referenced-by-count":33,"title":["Pre\u2010term delivery and periodontal disease: a case\u2013control study from Croatia"],"prefix":"10.1111","volume":"33","author":[{"given":"Andrija","family":"Bo\u0161njak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomislav","family":"Relja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanja","family":"Vu\u010di\u0107evi\u0107\u2010Boras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hrvoje","family":"Plasaj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darije","family":"Plan\u010dak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,8,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6979.2004.00461.x"},{"key":"e_1_2_7_3_1","unstructured":"Artukovi\u0107 D.(2001) Prevalence of periodontal diseases in adults in Zagreb area measured according to World Health Organization School of Dentistry Zagreb MSc Thesis (in Croatian)."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80734-9"},{"key":"e_1_2_7_5_1","first-page":"34","article-title":"Influence of cigarette smoking on vascular reaction during experimental gingivitis","volume":"96","author":"Bergstr\u00f6m J.","year":"1988","journal-title":"Scandinavian Journal of Dental Research"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2005.05.002"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00633.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00670.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200002243420802"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb01497.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"4652","DOI":"10.1128\/iai.62.10.4652-4655.1994","article-title":"Effects of Escherichia coli and Porphyromonas gingivalis lipopolysaccharides on pregnancy outcome in the golden hamster","volume":"62","author":"Collins J. 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