{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:10:50Z","timestamp":1790403050783,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,11,24]],"date-time":"2006-11-24T00:00:00Z","timestamp":1164326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives: <\/jats:bold> Report results of a randomized\u2010clinical trial of the efficacy of periodontal care in the improvement of glycemic control in 165 veterans with poorly controlled diabetes over 4 months.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> Outcomes were change in Haemoglobin A1c (HbA1c) in the Early Treatment <jats:italic>versus<\/jats:italic> untreated (Usual Care) groups and percent of participants with decreases in HbA1c. Analyses included simple\/multiple variable linear\/logistic regressions, adjusted for baseline HbA1c, age, and duration of diabetes.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Unadjusted analyses showed no differences between groups. After adjustment for baseline HbA1c, age, and diabetes duration, the mean absolute HbA1c change in the Early Treatment group was \u22120.65%<jats:italic>versus<\/jats:italic>\u22120.51% in the Usual Care group (<jats:italic>p<\/jats:italic>=0.47). Adjusted odds for improvement by 0.5% in the Early Treatment group was 1.67 (95% confidence interval: 0.84, 3.34, <jats:italic>p<\/jats:italic>=0.14). Usual Care subjects were twice as likely to increase insulin from baseline to 4 months (20%<jats:italic>versus<\/jats:italic> 11%, <jats:italic>p<\/jats:italic>=0.12) and less likely to decrease insulin (1%<jats:italic>versus<\/jats:italic> 6%, <jats:italic>p<\/jats:italic>=0.21) than Early Treatment subjects. Among insulin users at baseline, more increased insulin in the Usual Care group (40%<jats:italic>versus<\/jats:italic> 21%, <jats:italic>p<\/jats:italic>=0.06).<\/jats:p><jats:p><jats:bold>Conclusions: <\/jats:bold> No significant benefit was found for periodontal therapy after 4 months in this study; trends in some results were in favour of periodontal treatment.<\/jats:p>","DOI":"10.1111\/j.1600-051x.2006.01002.x","type":"journal-article","created":{"date-parts":[[2006,11,24]],"date-time":"2006-11-24T15:17:17Z","timestamp":1164381437000},"page":"46-52","source":"Crossref","is-referenced-by-count":138,"title":["Does periodontal care improve glycemic control? 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