{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:43:35Z","timestamp":1777563815992,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2006,11,8]],"date-time":"2006-11-08T00:00:00Z","timestamp":1162944000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background and Aim: <\/jats:bold> Specific microbial profiles that may distinguish between generalized aggressive\u2010periodontitis (GAgP) and generalized chronic\u2010periodontitis (GCP) have, to date, not been described. The purpose of the present study was to describe the subgingival microbial composition of Mexican subjects with GAgP and compare it with that of individuals with GCP and periodontal health (PH).<\/jats:p><jats:p><jats:bold>Material and Methods: <\/jats:bold> Seventy\u2010seven subjects with GAgP (<jats:italic>n<\/jats:italic>=19), GCP (<jats:italic>n<\/jats:italic>=39) and PH (<jats:italic>n<\/jats:italic>=19) were selected. Clinical measurements included plaque accumulation, gingival erythema, bleeding on probing, suppuration, pocket depth and attachment level. Up to 28 subgingival plaque samples were obtained from each subject and analysed using the checkerboard DNA\u2013DNA hybridization technique.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> GAgP and GCP subjects harboured significantly higher levels and\/or proportion of <jats:italic>Porphyromonas gingivalis<\/jats:italic>, <jats:italic>Tannerella forsythia<\/jats:italic> (levels: <jats:italic>p<\/jats:italic>&lt;0.001, proportion: <jats:italic>p<\/jats:italic>&lt;0.01), <jats:italic>Prevotella nigrescens<\/jats:italic> (<jats:italic>p<\/jats:italic>&lt;0.05 levels) and \u201cred\u201d complex species (<jats:italic>p<\/jats:italic>&lt;0.001 proportion) than PH subjects. All GAgP subjects were carriers of <jats:italic>P. gingivalis<\/jats:italic> and <jats:italic>P. nigrescens<\/jats:italic>. No significant differences in any of the 40 microbial species tested were detected between GAgP and GCP subjects.<\/jats:p><jats:p><jats:bold>Conclusions: <\/jats:bold> Our results revealed that the microbial differences between GAgP and GCP subjects were only discrete and none of the bacterial species tested seemed to specifically differentiate the subgingival microbial profile of either periodontitis group.<\/jats:p>","DOI":"10.1111\/j.1600-051x.2006.01006.x","type":"journal-article","created":{"date-parts":[[2006,11,8]],"date-time":"2006-11-08T08:42:07Z","timestamp":1162975327000},"page":"869-877","source":"Crossref","is-referenced-by-count":44,"title":["Subgingival microbiota of periodontally untreated Mexican subjects with generalized aggressive periodontitis"],"prefix":"10.1111","volume":"33","author":[{"given":"Laurie Ann","family":"Ximenez\u2010Fyvie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Argelia","family":"Almaguer\u2010Flores","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Velia","family":"Jacobo\u2010Soto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Lara\u2010Cordoba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jazmin\u2010Yunuen","family":"Moreno\u2010Borjas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eulalio","family":"Alcantara\u2010Maruri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,11,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.1"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1991.tb00462.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00644.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.6.803"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1997.tb00360.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1983.tb01278.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1128\/jcm.33.2.395-401.1995","article-title":"Evidence for absence in northern Europe of especially virulent clonal types of Actinobacillus actinomycetemcomitans","volume":"33","author":"Haubek D.","year":"1995","journal-title":"Journal of Clinical Microbiology"},{"key":"e_1_2_7_9_1","first-page":"113","article-title":"Isolation frequency and serotype distribution of mutans streptococci and Actinobacillus actinomycetemcomitans, and clinical periodontal status in Finnish and Vietnamese children","volume":"102","author":"Holtta P.","year":"1994","journal-title":"Scandinavian Journal of Dental Research"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0765.2002.01613.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.00289.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302x.2004.00161.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.9.1329"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1996.tb00541.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.29.s3.1.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1987.tb01595.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1993.tb00609.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.1.2"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1988.tb00999.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1998.tb02419.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1991.tb00070.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1999.tb00165.x"},{"key":"e_1_2_7_23_1","first-page":"788","article-title":"\u201cCheckerboard\u201d DNA\u2013DNA hybridization","volume":"17","author":"Socransky S. 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