{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T05:42:33Z","timestamp":1768023753983,"version":"3.49.0"},"reference-count":55,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2006,11,8]],"date-time":"2006-11-08T00:00:00Z","timestamp":1162944000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives: <\/jats:bold> To compare clinical outcomes of three different modalities of treatment for deep intra\u2010bony defects.<\/jats:p><jats:p><jats:bold>Material and methods: <\/jats:bold> Fifty\u2010six patients were paralleled for clinical parameters and randomly assigned to treatment. They displayed one angular defect each with an intra\u2010bony component 3\u2003mm, probing pocket depth (PPD) and probing attachment level (PAL) 7\u2003mm, and plaque index (PI) &lt;1. Nineteen defects were treated, respectively, with enamel matrix derivative (EMD)+tricalcium phosphate (TCP) or EMD alone and 18 defects with modified Widman flap (MWF). Primary flap closure was used in all three groups. PI, gingival index, bleeding on probing, PPD, PAL, and recession (REC) were measured before and 12 months after treatment.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Treatment with EMD alone yielded a 3.9\u00b11.3\u2003mm PPD decrease and a 3.7\u00b11.0\u2003mm PAL gain (<jats:italic>p<\/jats:italic>&lt;0.001), whereas EMD+<jats:italic>\u03b2<\/jats:italic>\u2010TCP produced a 4.1\u00b11.2\u2003mm PPD reduction and a 4.0\u00b11.0\u2003mm PAL gain (<jats:italic>p<\/jats:italic>&lt;0.001). These outcome parameters did not differ between the two groups. REC increased by 0.7\u00b11.3\u2003mm. After MWF treatment, attachment gain was 2.1\u00b11.4\u2003mm (<jats:italic>p<\/jats:italic>&lt;0.001) and PPD reduction was 3.8\u00b11.8\u2003mm, whereas REC increased by 1.5\u00b10.7\u2003mm (<jats:italic>p<\/jats:italic>=0.042 <jats:italic>versus<\/jats:italic> EMD).<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> Both EMD treatments showed similar clinical effects, with significant PAL gain and a significantly lower REC increase in comparison with MWF treatment.<\/jats:p>","DOI":"10.1111\/j.1600-051x.2006.01010.x","type":"journal-article","created":{"date-parts":[[2006,11,8]],"date-time":"2006-11-08T08:42:07Z","timestamp":1162975327000},"page":"885-893","source":"Crossref","is-referenced-by-count":53,"title":["Primary flap closure combined with Emdogain<sup>\u00ae<\/sup> alone or Emdogain<sup>\u00ae<\/sup> and Cerasorb<sup>\u00ae<\/sup> in the treatment of intra\u2010bony defects"],"prefix":"10.1111","volume":"33","author":[{"given":"Ivan","family":"Bokan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josip S.","family":"Bill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Schlagenhauf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,11,8]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"357","article-title":"Biomaterial resorption rate and healing site morphology of inorganic bovine and beta\u2010tricalcium phosphate in the canine","volume":"19","author":"Artzi Z.","year":"2004","journal-title":"International Journal of Oral Maxillofacial Implants"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-002-0185-0"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2001.281105.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2002.73.5.501"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.7.1043"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1995.66.4.261"},{"key":"e_1_2_6_8_1","first-page":"589","article-title":"The simplified papilla preservation flap. 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