{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:18:27Z","timestamp":1793395107548,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,11,20]],"date-time":"2006-11-20T00:00:00Z","timestamp":1163980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim: <\/jats:bold> Our aim was to measure the association of maternal periodontitis with low birth weight (LBW), pre\u2010term LBW, and intra\u2010uterine growth restriction.<\/jats:p><jats:p><jats:bold>Material and Methods: <\/jats:bold> An inclusive case\u2013control design including subjects examined for periodontitis through attachment loss, information on perinatal outcomes and general health. Data were analysed through conditional logistic regression.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Cases (<jats:italic>n<\/jats:italic>=304) and controls (<jats:italic>n<\/jats:italic>=611) had similar prevalence and severity of periodontitis, defined as at least three sites, in different teeth, with loss of three or more millimetres of clinical attachment level. Several factors were associated with the outcome, but the crude odds ratio for periodontitis was not significant. Odds ratio were 0.93 [95% confidence interval (CI): 0.63\u20131.41] for LBW and 0.92 (95% CI:0.54\u20131.57) for pre\u2010term LBW in the presence of periodontitis, after adjustment for maternal age, previous pregnancies, pre\u2010natal care, smoking, previous low birth or premature birth and other medical conditions, on a hierarchical model.<\/jats:p><jats:p><jats:bold>Conclusions: <\/jats:bold> Results do not support the hypothesis of association observed in previous studies after appropriate controlling for confounding variables. Negative peri\u2010natal outcomes are better explained by determinants other than periodontal health. This study adds to the growing body of literature on the relationship between periodontal diseases and systemic health.<\/jats:p>","DOI":"10.1111\/j.1600-051x.2006.01012.x","type":"journal-article","created":{"date-parts":[[2006,11,20]],"date-time":"2006-11-20T09:45:53Z","timestamp":1164015953000},"page":"31-39","source":"Crossref","is-referenced-by-count":70,"title":["Periodontal disease and perinatal outcomes: a case\u2010control study"],"prefix":"10.1111","volume":"34","author":[{"given":"D. G.","family":"Bassani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. T. 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