{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:16:00Z","timestamp":1791317760706,"version":"4.3.1"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2011,9,15]],"date-time":"2011-09-15T00:00:00Z","timestamp":1316044800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We investigated the association of periodontitis and severity of coronary artery disease (<jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content>) as verified using coronary angiography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Participants were recruited among those attending coronary angiography at Helsinki University Central Hospital, Finland, in 2007 and 2008. Detailed clinical periodontal examination [number of teeth, bleeding on probing, periodontal probing depth (<jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content>)] and oral panoramic radiographs [alveolar bone loss (<jats:styled-content style=\"fixed-case\">ABL<\/jats:styled-content>), angular bone defects] were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 506 patients, 123 (24.3%) had no significant <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content>, whereas 184 (36.4%) had stable <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content> and 169 (33.4%) acute coronary syndrome (<jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content>). Both stable <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content> were associated with 8\u201317 missing teeth with <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>s 4.33 (1.61\u201311.7, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.020) and 5.24 (1.90\u201314.5, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.014), and more than seven teeth with <jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content> \u22656\u00a0mm with <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>s 2.44 (1.01\u20136.07, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.049) and 2.75 (1.16\u20136.53, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.022) respectively. Severe <jats:styled-content style=\"fixed-case\">ABL<\/jats:styled-content> was associated with <jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content> with an <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 5.39 (1.23\u201323.6, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.025). Number of stenosed arteries was linearly associated with <jats:styled-content style=\"fixed-case\">ABL<\/jats:styled-content> (<jats:italic>p<\/jats:italic> for trend &lt;0.001), number of missing teeth (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), and pockets with probing depth \u22656\u00a0mm (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.033).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared with patients with no significant stenosis, poor periodontal health including missing teeth, periodontal inflammation, and bone loss is associated with angiographically verified coronary artery narrowing in patients with stable <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-051x.2011.01775.x","type":"journal-article","created":{"date-parts":[[2011,9,15]],"date-time":"2011-09-15T17:14:04Z","timestamp":1316106844000},"page":"1007-1014","source":"Crossref","is-referenced-by-count":73,"title":["Periodontitis is associated with angiographically verified coronary artery disease"],"prefix":"10.1111","volume":"38","author":[{"given":"K\u00e5re","family":"Buhlin","sequence":"first","affiliation":[{"name":"Institute of Dentistry University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e4ivi","family":"M\u00e4ntyl\u00e4","sequence":"additional","affiliation":[{"name":"Institute of Dentistry University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanna","family":"Paju","sequence":"additional","affiliation":[{"name":"Institute of Dentistry University of Helsinki Helsinki 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